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10.1186/s12884-021-03653-4

http://scihub22266oqcxt.onion/10.1186/s12884-021-03653-4
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33731037!7968137!33731037
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suck abstract from ncbi


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pmid33731037      BMC+Pregnancy+Childbirth 2021 ; 21 (1): 212
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  • Samba II PCR testing for COVID-19 in pregnant women: a retrospective cohort study and literature review #MMPMID33731037
  • Xu R; Pauley TA; Missfelder-Lobos H; Haddon RJ; Gupta RK; Chong HP
  • BMC Pregnancy Childbirth 2021[Mar]; 21 (1): 212 PMID33731037show ga
  • BACKGROUND: Asymptomatic carriage of COVID-19 in pregnant women has been reported and could lead to outbreaks in maternity units. We sought to ascertain the impact of rapid isothernal nucleic acid based testing for COVID-19 in an unselected cohort of pregnant women attending our maternity unit. We also assessed the correlation between community prevalence and asymptomatic carriage. METHODS: Data for the retrospective cohort study were collected from a large UK tertiary maternity unit over a 4-week period using computerised hospital records. Literature searches were performed across multiple repositories. COVID-19 prevalence was extracted from online repositories. RESULTS: Nasopharyngeal and oropharyngeal swabs were obtained from 457/465 (98%) women during the study period. The median turnaround time for results was 5.3 h (interquartile range (IQR) 2.6-8.9 h), with 92% of the results returned within 24 h. In our cohort, only one woman tested positive, giving a screen positive rate of 0.22% (1/457; 95% CI: 0.04-1.23%). One woman who tested negative developed a fever postnatally following discharge but was lost to follow-up. From our literature review, we did not find any correlation between asymptomatic carriage in pregnant women and the reported regional prevalence of COVID-19. CONCLUSIONS: Testing using the SAMBA-II machine was acceptable to the vast majority of pregnant women requiring admission and had a low turnaround time. Asymptomatic carriage is low, but not correlated to community prevalence rates. Screening pregnant women on admission will remain an important component in order to minimise nosocomial infection.
  • |COVID-19 Nucleic Acid Testing/*methods[MESH]
  • |COVID-19/*diagnosis/epidemiology[MESH]
  • |Carrier State/*diagnosis/epidemiology[MESH]
  • |Cohort Studies[MESH]
  • |Cross Infection/*prevention & control[MESH]
  • |Female[MESH]
  • |Hospitals, Maternity[MESH]
  • |Humans[MESH]
  • |Mass Screening[MESH]
  • |Point-of-Care Testing[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*diagnosis/epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |Time Factors[MESH]


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