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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Immune+Netw 2021 ; 21 (1): e4 Nephropedia Template TP
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Current Status of COVID-19 Vaccine Development: Focusing on Antigen Design and Clinical Trials on Later Stages #MMPMID33728097
Lee P; Kim CU; Seo SH; Kim DJ
Immune Netw 2021[Feb]; 21 (1): e4 PMID33728097show ga
The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.