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10.4110/in.2021.21.e2

http://scihub22266oqcxt.onion/10.4110/in.2021.21.e2
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33728095!7937509!33728095
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suck abstract from ncbi


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pmid33728095      Immune+Netw 2021 ; 21 (1): e2
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  • SARS-CoV-2-Specific T Cell Responses in Patients with COVID-19 and Unexposed Individuals #MMPMID33728095
  • Rha MS; Kim AR; Shin EC
  • Immune Netw 2021[Feb]; 21 (1): e2 PMID33728095show ga
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes coronavirus disease 2019 (COVID-19), an ongoing pandemic disease. In the current review, we describe SARS-CoV-2-specific CD4(+) and CD8(+) T-cell responses in acute and convalescent COVID-19 patients. We also discuss the relationships between COVID-19 severity and SARS-CoV-2-specific T-cell responses and summarize recent reports regarding SARS-CoV-2-reactive T cells in SARS-CoV-2-unexposed individuals. These T cells may be cross-reactive cells primed by previous infection with human common-cold coronaviruses. Finally, we outline SARS-CoV-2-specific T-cell responses in the context of vaccination. A better understanding of SARS-CoV-2-specific T-cell responses is needed to develop effective vaccines and therapeutics.
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