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10.1097/MD.0000000000024315

http://scihub22266oqcxt.onion/10.1097/MD.0000000000024315
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33725930!7982148!33725930
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suck abstract from ncbi

pmid33725930
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  • Co-infections of SARS-CoV-2 with multiple common respiratory pathogens in infected children: A retrospective study #MMPMID33725930
  • Li Y; Wang H; Wang F; Lu X; Du H; Xu J; Han F; Zhang L; Zhang M
  • Medicine (Baltimore) 2021[Mar]; 100 (11): e24315 PMID33725930show ga
  • ABSTRACT: Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, considerable attention has been paid on its epidemiology and clinical characteristics in children patients. However, it is also crucial for clinicians to summarize and investigate the co-infection of SARS-CoV-2 in children.We retrospectively reviewed the clinical manifestations, laboratory findings, and imaging characteristics of COVID-19 patients in co-infection group (CI, n = 27) and single infection group (SI, n = 54). Samples were tested for multiple pathogens.A high incidence (27/81, 33%) of co-infection in children with COVID-19 was revealed. The most frequent co-infected pathogen was mycoplasma pneumoniae (MP, 20/81, 25%), followed by virus (6/81, 7%), and bacteria (4/81, 5%). No significant difference in clinical characteristics, laboratory examinations, or hospital stay was observed between the patients with co-infections and those with monomicrobial, only lower in white blood cell counts (CI: 5.54 +/- 0.36 vs SI: 7.38 +/- 0.37, P = .002), neutrophil counts (CI: 2.20 +/- 0.20 vs SI: 2.92 +/- 0.23, P = .024) and lymphocyte counts (CI: 2.72 +/- 0.024 vs SI: 3.87 +/- 0.28, P = .006). Compared with the patients with monomicrobial, chest imaging of those with co-infections showed consolidation in more cases (CI: 29.6% vs SI: 11.1%, P = .038) and duration of positive in nucleic acid was shorter (CI: 6.69 +/- 0.82 vs SI: 9.69 +/- 0.74, P = .015).Co-infection was relatively common in children with COVID-19, almost 1/3 had co-infection, most commonly caused by MP. Co-infection did not cause a significant exacerbation in clinical manifestations.
  • |Adenoviridae Infections/epidemiology[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |China/epidemiology[MESH]
  • |Coinfection/*epidemiology/microbiology/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Influenza, Human/epidemiology[MESH]
  • |Leukocyte Count[MESH]
  • |Lymphocyte Count[MESH]
  • |Male[MESH]
  • |Moraxellaceae Infections/epidemiology[MESH]
  • |Mycoplasma pneumoniae[MESH]
  • |Pneumococcal Infections/epidemiology[MESH]
  • |Pneumonia, Mycoplasma/epidemiology[MESH]
  • |Respiratory Syncytial Virus Infections/epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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  • suck abstract from ncbi

    e24315 11.100 2021