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10.3201/eid2705.204688

http://scihub22266oqcxt.onion/10.3201/eid2705.204688
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33724916!8084500!33724916
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suck abstract from ncbi


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pmid33724916      Emerg+Infect+Dis 2021 ; 27 (5): 1323-1329
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  • Clinical Evaluation of Roche SD Biosensor Rapid Antigen Test for SARS-CoV-2 in Municipal Health Service Testing Site, the Netherlands #MMPMID33724916
  • Igloi Z; Velzing J; van Beek J; van de Vijver D; Aron G; Ensing R; Benschop K; Han W; Boelsums T; Koopmans M; Geurtsvankessel C; Molenkamp R
  • Emerg Infect Dis 2021[May]; 27 (5): 1323-1329 PMID33724916show ga
  • Rapid detection of infection is essential for stopping the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The Roche SD Biosensor rapid antigen test for SARS-CoV-2 was evaluated in a nonhospitalized symptomatic population. We rapid-tested a sample onsite and compared results with those from reverse transcription PCR and virus culture. We analyzed date of onset and symptoms using data from a clinical questionnaire. Overall test sensitivity was 84.9% (95% CI 79.1-89.4) and specificity was 99.5% (95% CI 98.7-99.8). Sensitivity increased to 95.8% (95% CI 90.5-98.2) for persons who sought care within 7 days of symptom onset. Test band intensity and time to result correlated strongly with viral load; thus, strong positive results could be read before the recommended time. Approximately 98% of all viable specimens with cycle threshold <30 were detected. Rapid antigen tests can detect symptomatic SARS-CoV-2 infections in the early phase of disease, thereby identifying the most infectious persons.
  • |*Biosensing Techniques[MESH]
  • |*COVID-19[MESH]
  • |Health Services[MESH]
  • |Humans[MESH]
  • |Netherlands/epidemiology[MESH]
  • |SARS-CoV-2[MESH]


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