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10.1016/j.jemermed.2021.01.041

http://scihub22266oqcxt.onion/10.1016/j.jemermed.2021.01.041
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33722414!7859730!33722414
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suck abstract from ncbi


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pmid33722414      J+Emerg+Med 2021 ; 60 (5): 615-625
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  • Lung Ultrasound vs Chest X-Ray Study for the Radiographic Diagnosis of COVID-19 Pneumonia in a High-Prevalence Population #MMPMID33722414
  • Gibbons RC; Magee M; Goett H; Murrett J; Genninger J; Mendez K; Tripod M; Tyner N; Costantino TG
  • J Emerg Med 2021[May]; 60 (5): 615-625 PMID33722414show ga
  • BACKGROUND: The viral illness severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), more commonly known as Coronavirus 2019 (COVID-19), has become a global pandemic, infecting over 100 million individuals worldwide. OBJECTIVES: The objective of this study was to compare the test characteristics of point-of-care lung ultrasound (LUS) with chest x-ray study (CXR) at radiographically detecting COVID-19 pneumonia. METHODS: This was a single-center, prospective, observational study at an urban university hospital with > 105,000 patient visits annually. Patients >/= 18 years old, who presented to the Emergency Department with predefined signs and symptoms of COVID-19, were eligible for enrollment. Each patient received an LUS using a portable, handheld ultrasound followed by a single-view, portable anteroposterior CXR. Patients with an abnormal LUS or CXR underwent a non-contrast-enhanced computed tomography scan (NCCT). The primary outcome was the radiographic diagnosis of COVID-19 pneumonia on NCCT. RESULTS: One hundred ten patients underwent LUS, CXR, and NCCT; 99 LUS and 73 CXRs were interpreted as positive; 81 NCCTs were interpreted as positive, providing a prevalence of COVID-19 pneumonia of 75% (95% confidence interval [CI] 66-83.2) in our study population. LUS sensitivity was 97.6% (95% CI 91.6-99.7) vs. 69.9% (95% CI 58.8-79.5) for CXR. LUS specificity was 33.3% (95% CI 16.5-54) vs. 44.4% (95% CI 25.5-64.7) for CXR. LUS positive predictive value and negative predictive value were 81.8% (95% CI 72.8-88.9) and 81.8% (95% CI 48.2-97.7), respectively, vs. 79.5% (95% CI 68.4-88), and 32.4% (95% CI 18-49.8), respectively, for CXR. CONCLUSION: LUS was more sensitive than CXR at radiographically identifying COVID-19 pneumonia.
  • |COVID-19 Nucleic Acid Testing[MESH]
  • |COVID-19/*diagnostic imaging/epidemiology/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasopharynx/virology[MESH]
  • |Pneumonia/diagnostic imaging[MESH]
  • |Point-of-Care Systems[MESH]
  • |Point-of-Care Testing[MESH]
  • |Prevalence[MESH]
  • |Prospective Studies[MESH]
  • |Radiography, Thoracic/*methods[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2/genetics/*isolation & purification[MESH]


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