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10.1177/11206721211001019

http://scihub22266oqcxt.onion/10.1177/11206721211001019
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33719624!ä!33719624

suck abstract from ncbi


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pmid33719624      Eur+J+Ophthalmol 2022 ; 32 (1): 628-636
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  • Optic nerve and macular optical coherence tomography in recovered COVID-19 patients #MMPMID33719624
  • Burgos-Blasco B; Guemes-Villahoz N; Vidal-Villegas B; Martinez-de-la-Casa JM; Donate-Lopez J; Martin-Sanchez FJ; Gonzalez-Armengol JJ; Porta-Etessam J; Martin JLR; Garcia-Feijoo J
  • Eur J Ophthalmol 2022[Jan]; 32 (1): 628-636 PMID33719624show ga
  • PURPOSE: To investigate the peripapillary retinal nerve fiber layer thickness (RNFLT), macular RNFLT, ganglion cell layer (GCL), and inner plexiform layer (IPL) thickness in recovered COVID-19 patients compared to controls. METHODS: Patients previously diagnosed with COVID-19 were included, while healthy patients formed the historic control group. All patients underwent an ophthalmological examination, including macular and optic nerve optical coherence tomography. In the case group, socio-demographic data, medical history, and neurological symptoms were collected. RESULTS: One hundred sixty patients were included; 90 recovered COVID-19 patients and 70 controls. COVID-19 patients presented increases in global RNFLT (mean difference 4.3; CI95% 0.8 to 7.7), nasal superior (mean difference 6.9; CI95% 0.4 to 13.4), and nasal inferior (mean difference 10.2; CI95% 2.4 to 18.1) sectors of peripapillary RNFLT. Macular RNFL showed decreases in COVID-19 patients in volume (mean difference -0.05; CI95% -0.08 to -0.02), superior inner (mean difference -1.4; CI95% -2.5 to -0.4), nasal inner (mean difference -1.1; CI95% -1.8 to -0.3), and nasal outer (mean difference -4.7; CI95% -7.0 to -2.4) quadrants. COVID-19 patients presented increased GCL thickness in volume (mean difference 0.04; CI95% 0.01 to 0.07), superior outer (mean difference 2.1; CI95% 0.8 to 3.3), nasal outer (mean difference 2.5; CI95% 1.1 to 4.0), and inferior outer (mean difference1.2; CI95% 0.1 to 2.4) quadrants. COVID-19 patients with anosmia and ageusia presented an increase in peripapillary RNFLT and macular GCL compared to patients without these symptoms. CONCLUSIONS: SARS-CoV-2 may affect the optic nerve and cause changes in the retinal layers once the infection has resolved.
  • |*COVID-19[MESH]
  • |*Tomography, Optical Coherence[MESH]
  • |Humans[MESH]
  • |Nerve Fibers[MESH]
  • |Optic Nerve[MESH]
  • |Retinal Ganglion Cells[MESH]


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