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10.1007/s42058-021-00058-2

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suck abstract from ncbi


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pmid33718774      Chin+J+Acad+Radiol 2021 ; 4 (1): 71-77
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  • The evolution of chest CT findings from admission to follow-up in 30 moderate to severe adult patients with COVID-19 pneumonia #MMPMID33718774
  • Zhou Y; Ren H; Wang S; You F; Feng L; Wang M; Wang J
  • Chin J Acad Radiol 2021[]; 4 (1): 71-77 PMID33718774show ga
  • OBJECTIVE: To analyze the evolution of chest computed tomography (CT) findings from admission to follow-up in moderate to severe patients with coronavirus disease-19 (COVID-19) pneumonia. METHODS: During December 2019-April 2020, the sequential CT images of 30 patients with COVID-19 pneumonia were retrospectively analyzed from admission to follow-up. The qualitative evolution tendency of lung abnormalities and semi-quantitative CT scores were analyzed for temporal change. RESULTS: The mean hospitalized period was 24.5 +/- 9.6 days (range 6-49 days). The average time from the first, second, third, fourth and follow-up CT examination to the initial symptom onset were 4.2 +/- 3.1 days, 10.7 +/- 4.4 days, 17.1 +/- 3.9 days, 24.6 +/- 7.5 days, and 42.4 +/- 15.6 days, respectively. During illness day 0-5, groundglass opacity (GGO) was the main pattern. The following illness day 6-11, the main CT pattern was consolidation and reticular pattern. The consolidation and reticular pattern gradually dissipate during illness day 12-23, and the reticular pattern and light GGO increased. When illness day was >/= 24 days, the reticular pattern and light GGO gradually decrease until complete dissipation. The highest CT score was at illness day 6-11. Pearson correlation analysis showed that the mean and maximum CT score were not correlated with the length of fever (r = 0.018, p = 0.923 and r = 0.086, p = 0.652) and hospitalization (r = 0.192, p = 0.31 and r = 0.273, p = 0.144). CONCLUSIONS: The dynamic evolution of CT manifestation in moderate to severe COVID-19 pneumonia patients followed a specific pattern over time. During illness day 6-11, the extent of lung abnormalities on chest CT was the most severe. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s42058-021-00058-2.
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