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10.1016/j.cytogfr.2021.03.001 http://scihub22266oqcxt.onion/10.1016/j.cytogfr.2021.03.001 33714693!7936752!33714693     free     free     free       Cytokine+Growth+Factor+Rev 2021 ; 60 (ä): 46-51 Nephropedia Template TP {{tp|p=33714693|t=2021. The conundrum of current anti-SARS-CoV-2 vaccines |pdf=|usr=}}{{33714693}} gab.com Text The conundrum of current anti-SARS-CoV-2 vaccines JO: Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=33714693 #FOAvip The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has given rise to the urgent need for vaccines and therapeutic interventions to address the spread of the SARS-CoV-2 virus. SARS-CoV-2 vaccines in development, and those being distributed currently, have been designed to induce neutralizing antibodies using the spike protein of the virus as an immunogen. However, the immunological correlates of protection against the virus remain unknown. This raises questions about the efficacy of current vaccination strategies. In addition, safety profiles of several vaccines seem inadequate or have not yet been evaluated under controlled experimentation. Here, evidence from the literature regarding the efforts already made to identify the immunological correlates of protection against SARS-CoV-2 infection are summarized. Furthermore, key biological features of most of the advanced vaccines and considerations regarding their safety and expected efficacy are highlighted. Twit Text FOAVip The conundrum of current anti-SARS-CoV-2 vaccines ????Cytokine Growth Factor Rev http://www.kidney.de/pget.php?&tw=1&pmid=33714693 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33714693 #FOAvip English Wikipedia <ref>{{Cite pmid|33714693}}</ref> The conundrum of current anti-SARS-CoV-2 vaccines #MMPMID33714693 Federico M Cytokine Growth Factor Rev 2021[Aug]; 60 (ä): 46-51 PMID33714693show ga The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has given rise to the urgent need for vaccines and therapeutic interventions to address the spread of the SARS-CoV-2 virus. SARS-CoV-2 vaccines in development, and those being distributed currently, have been designed to induce neutralizing antibodies using the spike protein of the virus as an immunogen. However, the immunological correlates of protection against the virus remain unknown. This raises questions about the efficacy of current vaccination strategies. In addition, safety profiles of several vaccines seem inadequate or have not yet been evaluated under controlled experimentation. Here, evidence from the literature regarding the efforts already made to identify the immunological correlates of protection against SARS-CoV-2 infection are summarized. Furthermore, key biological features of most of the advanced vaccines and considerations regarding their safety and expected efficacy are highlighted. |*Uncertainty[MESH] |Adenoviridae/genetics[MESH] |Animals[MESH] |Antibodies, Neutralizing/immunology[MESH] |COVID-19 Vaccines/genetics/*immunology[MESH] |COVID-19/*immunology/*prevention & control[MESH] |Genetic Vectors/genetics[MESH] |Humans[MESH] |SARS-CoV-2/*immunology[MESH] |Spike Glycoprotein, Coronavirus/immunology[MESH]The conundrum of current anti-SARS-CoV-2 vaccines (epmc).pdf DeepDyve Pubget Overpricing