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10.1038/s41467-021-21899-6 http://scihub22266oqcxt.onion/10.1038/s41467-021-21899-6 33712603!7955041!33712603     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33712603&cmd=llinks): Failed to open stream: HTTP request failed! 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Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic |pdf=|usr=}}{{33712603}} gab.com Text Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33712603 #FOAvip The role of school-based contacts in the epidemiology of SARS-CoV-2 is incompletely understood. We use an age-structured transmission model fitted to age-specific seroprevalence and hospital admission data to assess the effects of school-based measures at different time points during the COVID-19 pandemic in the Netherlands. Our analyses suggest that the impact of measures reducing school-based contacts depends on the remaining opportunities to reduce non-school-based contacts. If opportunities to reduce the effective reproduction number (R(e)) with non-school-based measures are exhausted or undesired and R(e) is still close to 1, the additional benefit of school-based measures may be considerable, particularly among older school children. As two examples, we demonstrate that keeping schools closed after the summer holidays in 2020, in the absence of other measures, would not have prevented the second pandemic wave in autumn 2020 but closing schools in November 2020 could have reduced R(e) below 1, with unchanged non-school-based contacts. Twit Text FOAVip Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33712603 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33712603 #FOAvip English Wikipedia <ref>{{Cite pmid|33712603}}</ref> Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic #MMPMID33712603 Rozhnova G; van Dorp CH; Bruijning-Verhagen P; Bootsma MCJ; van de Wijgert JHHM; Bonten MJM; Kretzschmar ME Nat Commun 2021[Mar]; 12 (1): 1614 PMID33712603show ga The role of school-based contacts in the epidemiology of SARS-CoV-2 is incompletely understood. We use an age-structured transmission model fitted to age-specific seroprevalence and hospital admission data to assess the effects of school-based measures at different time points during the COVID-19 pandemic in the Netherlands. Our analyses suggest that the impact of measures reducing school-based contacts depends on the remaining opportunities to reduce non-school-based contacts. If opportunities to reduce the effective reproduction number (R(e)) with non-school-based measures are exhausted or undesired and R(e) is still close to 1, the additional benefit of school-based measures may be considerable, particularly among older school children. As two examples, we demonstrate that keeping schools closed after the summer holidays in 2020, in the absence of other measures, would not have prevented the second pandemic wave in autumn 2020 but closing schools in November 2020 could have reduced R(e) below 1, with unchanged non-school-based contacts. |*Pandemics/prevention & control[MESH] |*SARS-CoV-2[MESH] |Adolescent[MESH] |Adult[MESH] |Age Factors[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Basic Reproduction Number/prevention & control/statistics & numerical data[MESH] |Bayes Theorem[MESH] |COVID-19/*epidemiology/*prevention & control/transmission[MESH] |Child[MESH] |Child, Preschool[MESH] |Cross-Sectional Studies[MESH] |Female[MESH] |Holidays[MESH] |Hospitalization[MESH] |Humans[MESH] |Infant[MESH] |Infant, Newborn[MESH] |Male[MESH] |Middle Aged[MESH] |Models, Biological[MESH] |Models, Statistical[MESH] |Netherlands/epidemiology[MESH] |Schools[MESH] |Seroepidemiologic Studies[MESH]Model-based evaluation of school- and non-school-related measures to c(epmc).pdf DeepDyve Pubget Overpricing