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10.1186/s13052-021-01016-5

http://scihub22266oqcxt.onion/10.1186/s13052-021-01016-5
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33712061!7953180!33712061
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suck abstract from ncbi


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pmid33712061      Ital+J+Pediatr 2021 ; 47 (1): 65
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  • Frequency of asymptomatic carriers of SARS-CoV-2 among children and adults after school reopening #MMPMID33712061
  • Milani GP; Marchisio P; Rocchi A; Bertolozzi G; Furlan L; La Vecchia A; Agostoni C; Costantino G
  • Ital J Pediatr 2021[Mar]; 47 (1): 65 PMID33712061show ga
  • BACKGROUND: Children often develop an asymptomatic form of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), but it is debated if children are at higher risk than adults to be asymptomatic carriers of SARS-CoV-2, especially during the school reopening. The main aim of this study was to investigate the frequency of SARS-CoV-2 asymptomatic carriers in children and adults during the reopening of the schools in Milan, Italy. METHODS: We conducted a cross-sectional study at the pediatric and adult Emergency Department (ED) of the Ca' Granda Ospedale Maggiore Policlinico (Milan) between October 1 and 31, 2020, i.e. 3 weeks after the reopening of schools. Patients admitted to the ED short stay observation and without any sign or symptom consistent with a SARS-CoV-2 were eligible. These patients underwent a nasopharyngeal swab specimen for the detection of SARS-CoV-2. The odds ratio and its 95% confidence interval (CI) was calculated to assess the risk of asymptomatically carrying the SARS-CoV-2 infection in children and adults. RESULTS: A total of 69 (27 females, median age 8.7 years) children and 251 (107 females, median age 71 years) adults were enrolled. Pediatric and adult subjects tested positive for SARS-CoV-2 with a similar frequency (1/69 [1.4%] vs 4/251 [1.6%]). Children had an odds ratio to be a carrier of 0.91 (CI 0.02- 9.38) compared to adults. CONCLUSIONS: The frequency of asymptomatic SARS-CoV-2 carriers was similar among children and adults. Considering the emerging diffusion of new SARS-CoV-2 variants, the asymptomatic spread of SARS-CoV-2 infection among children and adults should be monitored.
  • |Adolescent[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Carrier State/*diagnosis/epidemiology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Emergency Service, Hospital[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Italy/epidemiology[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasopharynx/virology[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]
  • |Schools[MESH]


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