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10.1177/03915603211001670

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33709828!10076152!33709828
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suck abstract from ncbi


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pmid33709828      Urologia 2023 ; 90 (1): 195-197
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  • Disease management in a patient diagnosed with COVID-19 disease during induction intravesical BCG therapy: A case report and review of the literature #MMPMID33709828
  • Ok F; Durmus E
  • Urologia 2023[Feb]; 90 (1): 195-197 PMID33709828show ga
  • OBJECTIVE: To discuss the patient diagnosed with COVID-19 disease while receiving intravesical induction bacillus Calmette-Guerin (BCG) treatment for non-muscle-invasive bladder cancer, its management in the light of the literature. PATIENT AND METHODS: A 52-year-old male patient, who received intravesical BCG treatment for high-grade pT1 papillary urothelial carcinoma, presented 12 h after taking the fourth dose of induction therapy 38.2 degrees fever and chills. The patient's reverse transcriptase-polymerase chain reaction test was positive, and Thorax CT imaging showed a few ground-glass pneumonic infiltrations in bilateral lung bases consistent with COVID-19 disease. RESULTS: Although international urology associations have current recommendations regarding the pandemic process, only one study has made specific recommendations regarding the patient group diagnosed with COVID-19 while receiving intravesical BCG treatment. According to this recommendation, we interrupted our patient's BCG treatment for 3 weeks and then completed the treatment for 6 weeks. A maintenance treatment not exceeding 1 year was planned. CONCLUSION: This group of patients' recommendation is to delay BCG therapy for at least 3 weeks after initial symptoms to allow for complete recovery. Although the administration schedule varies, maintenance therapy is recommended for no more than 1 year.
  • |*Adjuvants, Immunologic/therapeutic use[MESH]
  • |*BCG Vaccine/therapeutic use[MESH]
  • |*COVID-19/diagnosis[MESH]
  • |*Carcinoma, Transitional Cell/drug therapy/pathology[MESH]
  • |*Urinary Bladder Neoplasms/drug therapy/pathology[MESH]
  • |Administration, Intravesical[MESH]
  • |Disease Management[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neoplasm Invasiveness[MESH]


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