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10.1093/cid/ciab228

http://scihub22266oqcxt.onion/10.1093/cid/ciab228
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33709135!7989526!33709135
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suck abstract from ncbi


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pmid33709135      Clin+Infect+Dis 2021 ; 73 (6): e1261-e1269
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  • Household Severe Acute Respiratory Syndrome Coronavirus 2 Transmission and Children: A Network Prospective Study #MMPMID33709135
  • Soriano-Arandes A; Gatell A; Serrano P; Biosca M; Campillo F; Capdevila R; Fabrega A; Lobato Z; Lopez N; Moreno AM; Poblet M; Riera-Bosch MT; Rius N; Ruiz M; Sanchez A; Valldeperez C; Vila M; Pineda V; Lazcano U; Diaz Y; Reyes-Uruena J; Soler-Palacin P
  • Clin Infect Dis 2021[Sep]; 73 (6): e1261-e1269 PMID33709135show ga
  • BACKGROUND: The role of children in household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unclear. We describe the epidemiological and clinical characteristics of children with coronavirus disease 2019 (COVID-19) in Catalonia, Spain, and investigate the household transmission dynamics. METHODS: A prospective, observational, multicenter study was performed during summer and school periods (1 July 2020-31 October 2020) to analyze epidemiological and clinical features and viral household transmission dynamics in COVID-19 patients aged <16 years. A pediatric index case was established when a child was the first individual infected. Secondary cases were defined when another household member tested positive for SARS-CoV-2 before the child. The secondary attack rate (SAR) was calculated, and logistic regression was used to assess associations between transmission risk factors and SARS-CoV-2 infection. RESULTS: The study included 1040 COVID-19 patients. Almost half (47.2%) were asymptomatic, 10.8% had comorbidities, and 2.6% required hospitalization. No deaths were reported. Viral transmission was common among household members (62.3%). More than 70% (756/1040) of pediatric cases were secondary to an adult, whereas 7.7% (80/1040) were index cases. The SAR was significantly lower in households with COVID-19 pediatric index cases during the school period relative to summer (P = .02) and compared to adults (P = .006). No individual or environmental risk factors associated with the SAR. CONCLUSIONS: Children are unlikely to cause household COVID-19 clusters or be major drivers of the pandemic, even if attending school. Interventions aimed at children are expected to have a small impact on reducing SARS-CoV-2 transmission.
  • |*COVID-19[MESH]
  • |*SARS-CoV-2[MESH]
  • |Adult[MESH]
  • |Child[MESH]
  • |Family Characteristics[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]


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