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10.5005/jp-journals-10071-23722 http://scihub22266oqcxt.onion/10.5005/jp-journals-10071-23722 33707902!7922452!33707902     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Indian+J+Crit+Care+Med 2021 ; 25 (2): 215-218 Nephropedia Template TP {{tp|p=33707902|t=2021. Systemic Oxygen Utilization in Severe COVID-19 Respiratory Failure: A Case Series |pdf=|usr=}}{{33707902}} gab.com Text Systemic Oxygen Utilization in Severe COVID-19 Respiratory Failure: A Case Series JO: Indian J Crit Care Med http://www.kidney.de/pget.php?&tw=1&pmid=33707902 #FOAvip BACKGROUND: Management of hypoxemia in patients with severe COVID-19 respiratory failure is based on the guideline recommendations for specific SpO(2) targets. However, limited data exist on systemic O(2) utilization. The objective of this study was to examine systemic O(2) utilization in a case series of patients with this disease. PATIENTS AND METHODS: Between March 24, and April 9, 2020, 8 patients intubated for severe COVID-19 respiratory failure had near-simultaneous drawing of arterial blood gas (ABG), central venous blood gas (cVBG), and central venous oxygen saturation (ScvO(2)) at a mean of 6.1 days into hospitalization. Three patients were managed with indirect cardiac output (CO) monitoring by FloTrac sensor and Vigileo monitor (Edwards Lifesciences, Irvine, CA). The oxygen extraction index (OEI; SaO(2)-ScvO(2)/SaO(2)) and oxygen extraction fraction (OEF; CaO(2)-CvO(2)/CaO(2) >/= 100) were calculated. Values for hyperoxia (ScvO(2) >/= 90%), normoxia (ScvO(2) 71-89%), and hypoxia (ScvO(2) </= 70%) were based on the literature. Mean values were calculated. RESULTS: The mean partial pressure of oxygen (PaO(2)) was 102 with a mean fraction of inspired O(2) (FiO(2)) of 44%. One patient was hyperoxic with a reduced OEI (17%). Five patients were normoxic, but 2 had a reduced OEF (mean 15.9%). Two patients were hypoxic but had increased systemic O(2) utilization based on OEF or OEI. CONCLUSION: In select patients with severe COVID-19 respiratory failure, O(2) delivery (DO(2)) was found to exceed O(2) utilization. SpO(2) targets based on systemic O(2) utilization may help in reducing oxygen toxicity, especially in the absence of anaerobic metabolism. Further data are needed on the prevalence of systemic O(2) utilization in COVID-19. HOW TO CITE THIS ARTICLE: Garg RK, Kimbrough T, Lodhi W, DaSilva I. Systemic Oxygen Utilization in Severe COVID-19 Respiratory Failure: A Case Series. Indian J Crit Care Med 2021;25(2):215-218. Twit Text FOAVip Systemic Oxygen Utilization in Severe COVID-19 Respiratory Failure: A Case Series ????Indian J Crit Care Med http://www.kidney.de/pget.php?&tw=1&pmid=33707902 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33707902 #FOAvip English Wikipedia <ref>{{Cite pmid|33707902}}</ref> Systemic Oxygen Utilization in Severe COVID-19 Respiratory Failure: A Case Series #MMPMID33707902 Garg RK; Kimbrough T; Lodhi W; DaSilva I Indian J Crit Care Med 2021[Feb]; 25 (2): 215-218 PMID33707902show ga BACKGROUND: Management of hypoxemia in patients with severe COVID-19 respiratory failure is based on the guideline recommendations for specific SpO(2) targets. However, limited data exist on systemic O(2) utilization. The objective of this study was to examine systemic O(2) utilization in a case series of patients with this disease. PATIENTS AND METHODS: Between March 24, and April 9, 2020, 8 patients intubated for severe COVID-19 respiratory failure had near-simultaneous drawing of arterial blood gas (ABG), central venous blood gas (cVBG), and central venous oxygen saturation (ScvO(2)) at a mean of 6.1 days into hospitalization. Three patients were managed with indirect cardiac output (CO) monitoring by FloTrac sensor and Vigileo monitor (Edwards Lifesciences, Irvine, CA). The oxygen extraction index (OEI; SaO(2)-ScvO(2)/SaO(2)) and oxygen extraction fraction (OEF; CaO(2)-CvO(2)/CaO(2) >/= 100) were calculated. Values for hyperoxia (ScvO(2) >/= 90%), normoxia (ScvO(2) 71-89%), and hypoxia (ScvO(2) äSystemic Oxygen Utilization in Severe COVID-19 Respiratory Failure: A (epmc).pdf DeepDyve Pubget Overpricing