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suck abstract from ncbi


10.1038/s41598-021-84842-1

http://scihub22266oqcxt.onion/10.1038/s41598-021-84842-1
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33707476!7952405!33707476
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suck abstract from ncbi


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pmid33707476      Sci+Rep 2021 ; 11 (1): 5626
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  • Microbicidal actives with virucidal efficacy against SARS-CoV-2 and other beta- and alpha-coronaviruses and implications for future emerging coronaviruses and other enveloped viruses #MMPMID33707476
  • Ijaz MK; Nims RW; Zhou SS; Whitehead K; Srinivasan V; Kapes T; Fanuel S; Epstein JH; Daszak P; Rubino JR; McKinney J
  • Sci Rep 2021[Mar]; 11 (1): 5626 PMID33707476show ga
  • Mitigating the risk of acquiring coronaviruses including SARS-CoV-2 requires awareness of the survival of virus on high-touch environmental surfaces (HITES) and skin, and frequent use of targeted microbicides with demonstrated efficacy. The data on stability of infectious SARS-CoV-2 on surfaces and in suspension have been put into perspective, as these inform the need for hygiene. We evaluated the efficacies of formulated microbicidal actives against alpha- and beta-coronaviruses, including SARS-CoV-2. The coronaviruses SARS-CoV, SARS-CoV-2, human coronavirus 229E, murine hepatitis virus-1, or MERS-CoV were deposited on prototypic HITES or spiked into liquid matrices along with organic soil loads. Alcohol-, quaternary ammonium compound-, hydrochloric acid-, organic acid-, p-chloro-m-xylenol-, and sodium hypochlorite-based microbicidal formulations were evaluated per ASTM International and EN standard methodologies. All evaluated formulated microbicides inactivated SARS-CoV-2 and other coronaviruses in suspension or on prototypic HITES. Virucidal efficacies (>/= 3 to >/= 6 log(10) reduction) were displayed within 30 s to 5 min. The virucidal efficacy of a variety of commercially available formulated microbicides against SARS-CoV-2 and other coronaviruses was confirmed. These microbicides should be useful for targeted surface and hand hygiene and disinfection of liquids, as part of infection prevention and control for SARS-CoV-2 and emerging mutational variants, and other emerging enveloped viruses.
  • |*Alphacoronavirus[MESH]
  • |*Anti-Infective Agents[MESH]
  • |*SARS-CoV-2[MESH]
  • |Animals[MESH]
  • |Half-Life[MESH]
  • |Humans[MESH]
  • |Microbial Sensitivity Tests[MESH]


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