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10.1080/14767058.2021.1900105 http://scihub22266oqcxt.onion/10.1080/14767058.2021.1900105 33706649!?!33706649 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33706649&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Matern+Fetal+Neonatal+Med 2021 ; 34 (21): 3601-3608 Nephropedia Template TP {{tp|p=33706649|t=2021. The effect of real-time polymerase chain reaction cycle threshold values on perinatal outcomes of pregnant women with COVID-19 |pdf=|usr=}}{{33706649}} gab.com Text The effect of real-time polymerase chain reaction cycle threshold values on perinatal outcomes of pregnant women with COVID-19 JO: J Matern Fetal Neonatal Med http://www.kidney.de/pget.php?&tw=1&pmid=33706649 #FOAvip OBJECTIVE: To evaluate the effect of cycle threshold (Ct) values on the pregnancy outcomes of women with coronavirus disease 2019 (COVID-19). MATERIALS AND METHODS: This prospective cohort study was conducted on pregnant women with COVID-19. A real-time polymerase chain reaction (RT-PCR) assay of a nasopharyngeal and oropharyngeal specimen was used for the diagnosis. Initial Ct values for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RT-PCR tests were recorded. 22.9 was the 50th percentile Ct value of the study population. The study population was divided into two groups based on their Ct values: (1) Cases with Higher Ct values (Ct > 22.9)(n = 50) and (2) Cases with lower Ct values (Ct </= 22.9)(n = 55). Demographic features, clinical characteristics, disease progression, laboratory test results and pregnancy outcomes were compared between the groups. A receiver operating characteristic (ROC) curve was used to assess the performance of Ct values in predicting obstetric complications. RESULTS: Obstetric complication rate was significantly higher in cases with lower Ct values (p < .001). A significantly lower lymphocyte count together with higher ESR, procalcitonin and IL-6 values were observed in the cases with lower Ct values (p > .05). Additionally, a significantly higher NICU admission rate and longer hospital stays were present in the cases with lower Ct values (p > .05). The value in ROC curves with the best balance of sensitivity/specificity was 22.5 (85.7% sensitivity, 63.6% specificity). CONCLUSION: Lower Ct values may be associated with an increased rate of obstetric complications in pregnant women with COVID-19. Physicians should be cautious in the management of cases with Ct levels below 22.5. Twit Text FOAVip The effect of real-time polymerase chain reaction cycle threshold values on perinatal outcomes of pregnant women with COVID-19 ????J Matern Fetal Neonatal Med http://www.kidney.de/pget.php?&tw=1&pmid=33706649 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33706649 #FOAvip English Wikipedia <ref>{{Cite pmid|33706649}}</ref> The effect of real-time polymerase chain reaction cycle threshold values on perinatal outcomes of pregnant women with COVID-19 #MMPMID33706649 Tanacan A; Anuk AT; Erol SA; Keskin HL; Altinboga O; Yakistiran B; Aydogan S; Unlu S; Eyi EGY; Tayman C; Dinc B; Sahin D; Moraloglu Tekin O J Matern Fetal Neonatal Med 2021[Nov]; 34 (21): 3601-3608 PMID33706649show ga OBJECTIVE: To evaluate the effect of cycle threshold (Ct) values on the pregnancy outcomes of women with coronavirus disease 2019 (COVID-19). MATERIALS AND METHODS: This prospective cohort study was conducted on pregnant women with COVID-19. A real-time polymerase chain reaction (RT-PCR) assay of a nasopharyngeal and oropharyngeal specimen was used for the diagnosis. Initial Ct values for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RT-PCR tests were recorded. 22.9 was the 50th percentile Ct value of the study population. The study population was divided into two groups based on their Ct values: (1) Cases with Higher Ct values (Ct > 22.9)(n = 50) and (2) Cases with lower Ct values (Ct .05). Additionally, a significantly higher NICU admission rate and longer hospital stays were present in the cases with lower Ct values (p > .05). The value in ROC curves with the best balance of sensitivity/specificity was 22.5 (85.7% sensitivity, 63.6% specificity). CONCLUSION: Lower Ct values may be associated with an increased rate of obstetric complications in pregnant women with COVID-19. Physicians should be cautious in the management of cases with Ct levels below 22.5. |*COVID-19[MESH] |*Pregnant People[MESH] |Female[MESH] |Humans[MESH] |Pregnancy[MESH] |Prospective Studies[MESH] |Real-Time Polymerase Chain Reaction[MESH]The effect of real-time polymerase chain reaction cycle threshold valu(epmc).pdf DeepDyve Pubget Overpricing