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10.1002/cpt.2207 http://scihub22266oqcxt.onion/10.1002/cpt.2207 33705574!8048882!33705574     free     free     free       Clin+Pharmacol+Ther 2021 ; 109 (4): 987-999 Nephropedia Template TP {{tp|p=33705574|t=2021. Vaccines: Underlying Principles of Design and Testing |pdf=|usr=}}{{33705574}} gab.com Text Vaccines: Underlying Principles of Design and Testing JO: Clin Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=33705574 #FOAvip In this paper, we review the key elements that should be considered to take a novel vaccine from the laboratory through to licensure in the modern era. This paper is divided into four sections. First, we discuss the host immune responses that we engage with vaccines. Second, we discuss how in vivo and in vitro studies can inform vaccine design. Third, we discuss different vaccine modalities that have been licensed or are in testing in humans. Last, we overview the basic principles of vaccine approvals. Throughout we provide real-world examples of vaccine development against infectious diseases, including coronavirus disease 2019 (COVID-19). Twit Text FOAVip Vaccines: Underlying Principles of Design and Testing ????Clin Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=33705574 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33705574 #FOAvip English Wikipedia <ref>{{Cite pmid|33705574}}</ref> Vaccines: Underlying Principles of Design and Testing #MMPMID33705574 Kallon S; Samir S; Goonetilleke N Clin Pharmacol Ther 2021[Apr]; 109 (4): 987-999 PMID33705574show ga In this paper, we review the key elements that should be considered to take a novel vaccine from the laboratory through to licensure in the modern era. This paper is divided into four sections. First, we discuss the host immune responses that we engage with vaccines. Second, we discuss how in vivo and in vitro studies can inform vaccine design. Third, we discuss different vaccine modalities that have been licensed or are in testing in humans. Last, we overview the basic principles of vaccine approvals. Throughout we provide real-world examples of vaccine development against infectious diseases, including coronavirus disease 2019 (COVID-19). |Adjuvants, Immunologic/pharmacology[MESH] |Drug Approval/*organization & administration[MESH] |Drug Design[MESH] |Drug Evaluation, Preclinical[MESH] |Immunity, Herd/immunology[MESH] |Immunity, Innate/immunology[MESH] |Public Health[MESH] |United States[MESH] |United States Food and Drug Administration[MESH]Vaccines: Underlying Principles of Design and Testing (epmc).pdf DeepDyve Pubget Overpricing