Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1093/jmcb/mjab016 http://scihub22266oqcxt.onion/10.1093/jmcb/mjab016 33693723!7989365!33693723     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Mol+Cell+Biol 2021 ; 13 (3): 175-184 Nephropedia Template TP {{tp|p=33693723|t=2021. What makes (hydroxy)chloroquine ineffective against COVID-19: insights from cell biology |pdf=|usr=}}{{33693723}} gab.com Text What makes (hydroxy)chloroquine ineffective against COVID-19: insights from cell biology JO: J Mol Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=33693723 #FOAvip Since chloroquine (CQ) and hydroxychloroquine (HCQ) can inhibit the invasion and proliferation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in cultured cells, the repurposing of these antimalarial drugs was considered a promising strategy for treatment and prevention of coronavirus disease (COVID-19). However, despite promising preliminary findings, many clinical trials showed neither significant therapeutic nor prophylactic benefits of CQ and HCQ against COVID-19. Here, we aim to answer the question of why these drugs are not effective against the disease by examining the cellular working mechanisms of CQ and HCQ in prevention of SARS-CoV-2 infections. Twit Text FOAVip What makes (hydroxy)chloroquine ineffective against COVID-19: insights from cell biology ????J Mol Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=33693723 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33693723 #FOAvip English Wikipedia <ref>{{Cite pmid|33693723}}</ref> What makes (hydroxy)chloroquine ineffective against COVID-19: insights from cell biology #MMPMID33693723 Altulea D; Maassen S; Baranov MV; van den Bogaart G J Mol Cell Biol 2021[Jul]; 13 (3): 175-184 PMID33693723show ga Since chloroquine (CQ) and hydroxychloroquine (HCQ) can inhibit the invasion and proliferation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in cultured cells, the repurposing of these antimalarial drugs was considered a promising strategy for treatment and prevention of coronavirus disease (COVID-19). However, despite promising preliminary findings, many clinical trials showed neither significant therapeutic nor prophylactic benefits of CQ and HCQ against COVID-19. Here, we aim to answer the question of why these drugs are not effective against the disease by examining the cellular working mechanisms of CQ and HCQ in prevention of SARS-CoV-2 infections. |*COVID-19 Drug Treatment[MESH] |Antiviral Agents/therapeutic use[MESH] |COVID-19/virology[MESH] |Cell Proliferation/drug effects[MESH] |Chloroquine/adverse effects/*therapeutic use[MESH] |Drug Repositioning[MESH] |Humans[MESH] |Hydroxychloroquine/adverse effects/*therapeutic use[MESH]What makes (hydroxy)chloroquine ineffective against COVID-19: insights(epmc).pdf DeepDyve Pubget Overpricing