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10.1093/ehjci/jeab042

http://scihub22266oqcxt.onion/10.1093/ehjci/jeab042
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33686389!7989521!33686389
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suck abstract from ncbi

pmid33686389      Eur+Heart+J+Cardiovasc+Imaging 2021 ; 22 (8): 844-851
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  • Early cardiac involvement in patients with acute COVID-19 infection identified by multiparametric cardiovascular magnetic resonance imaging #MMPMID33686389
  • Chen BH; Shi NN; Wu CW; An DA; Shi YX; Wesemann LD; Hu J; Xu JR; Shan F; Wu LM
  • Eur Heart J Cardiovasc Imaging 2021[Jul]; 22 (8): 844-851 PMID33686389show ga
  • AIMS: In order to determine acute cardiac involvement in patients with COVID-19, we quantitatively evaluated tissue characteristics and mechanics by non-invasive cardiac magnetic resonance (CMR) in a cohort of patients within the first 10 days of the onset of COVID symptoms. METHODS AND RESULTS: Twenty-five patients with reverse transcription polymerase chain reaction confirmed COVID-19 and at least one marker of cardiac involvement [cardiac symptoms, abnormal electrocardiograph (ECG), or abnormal cardiac biomarkers] and 25 healthy age- and gender-matched control subjects were recruited to the study. Patients were divided into those with elevated (n = 8) or normal TnI (n = 17). There were significant differences in global longitudinal strain among patients who were positive and negative for hs-TnI, and controls [-12.3 (-13.3, -11.5)%, -13.1 (-14.2, -9.8)%, and -15.7 (-18.3, -12.7)%, P = 0.004]. Native myocardial T1 relaxation times in patients with positive and negative hs-TnI manifestation (1169.8 +/- 12.9 and 1113.2 +/- 31.2 ms) were significantly higher than the normal (1065 +/- 57 ms) subjects, respectively (P < 0.001). The extracellular volume (ECV) of patients who were positive and negative for hs-TnI was higher than that of the normal controls [32 (31, 33)%, 29 (27, 30)%, and 26 (24, 27.5)%, P < 0.001]. In our study, quantitative T2 mapping in patients who were positive and negative for hs-TnI [51 (47.9, 52.8) and 48 (47, 49.4) ms] was significantly higher than the normal [42 (41, 45.2) ms] subjects (P < 0.001). CONCLUSION: In patients with early-stage COVID-19, myocardial oedema, and functional abnormalities are a frequent finding, while irreversible regional injury such as necrosis may be infrequent.
  • |*COVID-19[MESH]
  • |Case-Control Studies[MESH]
  • |Humans[MESH]
  • |Magnetic Resonance Imaging[MESH]
  • |Magnetic Resonance Imaging, Cine[MESH]
  • |Myocardium[MESH]
  • |Predictive Value of Tests[MESH]
  • |Prospective Studies[MESH]


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