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10.1080/03602532.2021.1895204 http://scihub22266oqcxt.onion/10.1080/03602532.2021.1895204 33683968!7989954!33683968     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Drug+Metab+Rev 2021 ; 53 (4): 478-490 Nephropedia Template TP {{tp|p=33683968|t=2021. In quest of a new therapeutic approach in COVID-19: the endocannabinoid system |pdf=|usr=}}{{33683968}} gab.com Text In quest of a new therapeutic approach in COVID-19: the endocannabinoid system JO: Drug Metab Rev http://www.kidney.de/pget.php?&tw=1&pmid=33683968 #FOAvip The SARS-Cov-2 virus caused a high morbidity and mortality rate disease, that is the COVID-19 pandemic. Despite the unprecedented research interest in this field, the lack of specific treatments leads to severe complications in a high number of cases. Current treatment includes antivirals, corticosteroids, immunoglobulins, antimalarials, interleukin-6 inhibitors, anti-GM-CSF, convalescent plasma, immunotherapy, antibiotics, circulation support, oxygen therapy, and circulation support. Due to the limited results, until specific treatments are available, other therapeutic approaches need to be considered. The endocannabinoid system is found in multiple systems within the human body, including the immune system. Its activation can lead to beneficial results such as decreased viral entry, decreased viral replication, and a decrease in pro-inflammatory cytokines such as IL-2, IL-4, IL-6, IL-12, TNF-alpha, or IFN-gamma. Moreover, endocannabinoid system activation can lead to an increase in anti-inflammatory cytokines, mainly represented by IL-10. Overall, the cannabinoid system can potentially reduce pulmonary inflammation, increase the immunomodulatory effect, decrease PMN infiltration, reduce fibrosis, and decrease viral replication, as well as decrease the 'cytokine storm'. Although the cannabinoid system has many mechanisms to provide certain benefits in the treatment of SARS-CoV-2 infected patients, research in this field is needed for a better understanding of the cannabinoid impact in this situation. Twit Text FOAVip In quest of a new therapeutic approach in COVID-19: the endocannabinoid system ????Drug Metab Rev http://www.kidney.de/pget.php?&tw=1&pmid=33683968 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33683968 #FOAvip English Wikipedia <ref>{{Cite pmid|33683968}}</ref> In quest of a new therapeutic approach in COVID-19: the endocannabinoid system #MMPMID33683968 Lucaciu O; Aghiorghiesei O; Petrescu NB; Mirica IC; Benea HRC; Apostu D Drug Metab Rev 2021[Nov]; 53 (4): 478-490 PMID33683968show ga The SARS-Cov-2 virus caused a high morbidity and mortality rate disease, that is the COVID-19 pandemic. Despite the unprecedented research interest in this field, the lack of specific treatments leads to severe complications in a high number of cases. Current treatment includes antivirals, corticosteroids, immunoglobulins, antimalarials, interleukin-6 inhibitors, anti-GM-CSF, convalescent plasma, immunotherapy, antibiotics, circulation support, oxygen therapy, and circulation support. Due to the limited results, until specific treatments are available, other therapeutic approaches need to be considered. The endocannabinoid system is found in multiple systems within the human body, including the immune system. Its activation can lead to beneficial results such as decreased viral entry, decreased viral replication, and a decrease in pro-inflammatory cytokines such as IL-2, IL-4, IL-6, IL-12, TNF-alpha, or IFN-gamma. Moreover, endocannabinoid system activation can lead to an increase in anti-inflammatory cytokines, mainly represented by IL-10. Overall, the cannabinoid system can potentially reduce pulmonary inflammation, increase the immunomodulatory effect, decrease PMN infiltration, reduce fibrosis, and decrease viral replication, as well as decrease the 'cytokine storm'. Although the cannabinoid system has many mechanisms to provide certain benefits in the treatment of SARS-CoV-2 infected patients, research in this field is needed for a better understanding of the cannabinoid impact in this situation. |*COVID-19/therapy[MESH] |*Endocannabinoids[MESH] |COVID-19 Serotherapy[MESH] |Humans[MESH] |Immunization, Passive[MESH] |Pandemics[MESH]In quest of a new therapeutic approach in COVID-19: the endocannabinoi(epmc).pdf DeepDyve Pubget Overpricing