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10.3233/THC-218027

http://scihub22266oqcxt.onion/10.3233/THC-218027
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33682766!8158053!33682766
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suck abstract from ncbi


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pmid33682766      Technol+Health+Care 2021 ; 29 (S1): 297-309
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  • Temporal changes of quantitative CT findings from 102 patients with COVID-19 in Wuhan, China: A longitudinal study #MMPMID33682766
  • Chen X; Sun W; Xu D; Ma J; Xiao F; Xu H
  • Technol Health Care 2021[]; 29 (S1): 297-309 PMID33682766show ga
  • BACKGROUND: Computed tomography (CT) imaging combined with artificial intelligence is important in the diagnosis and prognosis of lung diseases. OBJECTIVE: This study aimed to investigate temporal changes of quantitative CT findings in patients with COVID-19 in three clinic types, including moderate, severe, and non-survivors, and to predict severe cases in the early stage from the results. METHODS: One hundred and two patients with confirmed COVID-19 were included in this study. Based on the time interval between onset of symptoms and the CT scan, four stages were defined in this study: Stage-1 (0 approximately 7 days); Stage-2 (8 approximately 14 days); Stage-3 (15 approximately 21days); Stage-4 (> 21 days). Eight parameters, the infection volume and percentage of the whole lung in four different Hounsfield (HU) ranges, ((-, -750), [-750, -300), [-300, 50) and [50, +)), were calculated and compared between different groups. RESULTS: The infection volume and percentage of four HU ranges peaked in Stage-2. The highest proportion of HU [-750, 50) was found in the infected regions in non-survivors among three groups. CONCLUSIONS: The findings indicate rapid deterioration in the first week since the onset of symptoms in non-survivors. Higher proportion of HU [-750, 50) in the lesion area might be a potential bio-marker for poor prognosis in patients with COVID-19.
  • |*Artificial Intelligence[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*diagnostic imaging/mortality/*physiopathology[MESH]
  • |China[MESH]
  • |Comorbidity[MESH]
  • |Disease Progression[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Time Factors[MESH]


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