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10.1007/s10067-021-05675-x

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suck abstract from ncbi


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pmid33677725      Clin+Rheumatol 2021 ; 40 (5): 2057-2063
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  • The impact of SARS-CoV-2 coronavirus infection in patients with systemic lupus erythematosus from a single center in Catalonia #MMPMID33677725
  • Espinosa G; Prieto-Gonzalez S; Llevadot M; Marco-Hernandez J; Martinez-Artuna A; Perez-Isidro A; Rife E; Cervera R
  • Clin Rheumatol 2021[May]; 40 (5): 2057-2063 PMID33677725show ga
  • OBJECTIVE: To evaluate the incidence and characteristics of SARS-CoV-2 infection among patients with systemic lupus erythematosus (SLE) and to compare it to that described in the general population. METHODS: For 5 weeks, we carried out a cross-sectional study consisting of telephone interviews of SLE patients. We collected epidemiological data, symptoms suggesting COVID-19, results of nasopharyngeal swabs, and ongoing treatments. In those patients who required hospital admission, clinical, radiological, and laboratory features, and outcome were investigated. RESULTS: Four hundred patients with SLE completed the survey. Overall, 4 (1.00%, 95%CI 0.02-1.98) patients were classified as confirmed cases of COVID-19 and 26 (6.51%, 95%CI 4.08-8.94) as possible clinical cases. The incidence of confirmed cases in our series was similar to that of the Catalan population (1.00% versus 0.63%; p = 0.456), whereas the incidence of possible cases was higher in our series (6.51% versus 1.29%; p < 0.005). The only difference between SLE patients with confirmed and possible COVID-19 and those without was the percentage of patients who have had contact with a confirmed or possible case of COVID-19 (26.7% versus 9.2%; p = 0.003) CONCLUSIONS: The incidence of COVID-19 in SLE patients with inactive disease is low and, in our series, all cases with confirmed infection recovered. Key Points * In a cohort of SLE patients with stable and clinical inactive disease, the incidence of COVID-19 is low. * All SLE patients with confirmed SARS-CoV-2 infection recovered.
  • |*COVID-19[MESH]
  • |*Lupus Erythematosus, Systemic/complications/epidemiology[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Humans[MESH]
  • |SARS-CoV-2[MESH]


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