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10.1016/j.tracli.2021.02.005

http://scihub22266oqcxt.onion/10.1016/j.tracli.2021.02.005
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33675992!7927574!33675992
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suck abstract from ncbi


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pmid33675992      Transfus+Clin+Biol 2021 ; 28 (2): 132-134
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  • Impact of pathogen-reduction technologies on COVID-19 convalescent plasma potency #MMPMID33675992
  • Focosi D; Franchini M
  • Transfus Clin Biol 2021[May]; 28 (2): 132-134 PMID33675992show ga
  • Pathogen reduction technologies (PRT) have been recommended by many regulatory authorities to minimize the residual risk of transfusion-transmitted infections associated with COVID19 convalescent plasma. While its impact on safety and its cost-effectiveness are nowadays well proven, there is theoretical concern that PRT could impact efficacy of convalescent plasma by altering concentration and/or function of the neutralizing antibodies (nAb). We review here the evidence supporting a lack of significant detrimental effect from PRTs on nAbs.
  • |Antibodies, Neutralizing/blood[MESH]
  • |COVID-19 Serotherapy[MESH]
  • |COVID-19/blood/*therapy[MESH]
  • |Humans[MESH]
  • |Immunization, Passive/adverse effects[MESH]
  • |Infection Control/*methods[MESH]
  • |Transfusion Reaction/*prevention & control[MESH]


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