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10.37201/req/018.2021

http://scihub22266oqcxt.onion/10.37201/req/018.2021
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33675220!8019465!33675220
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suck abstract from ncbi


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pmid33675220      Rev+Esp+Quimioter 2021 ; 34 (2): 136-140
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  • Real-life use of remdesivir in hospitalized patients with COVID-19 #MMPMID33675220
  • Garcia-Vidal C; Meira F; Cozar-Llisto A; Duenas G; Puerta-Alcalde P; Garcia-Pouton N; Chumbita M; Cardozo C; Hernandez-Meneses M; Alonso-Navarro R; Rico V; Aguero D; Bodro M; Morata L; Jordan C; Lopera C; Ambrosioni J; Segui F; Grafia N; Castro P; Garcia F; Mensa J; Martinez JA; Sanjuan G; Soriano A
  • Rev Esp Quimioter 2021[Apr]; 34 (2): 136-140 PMID33675220show ga
  • OBJECTIVE: Controversial results on remdesivir efficacy have been reported. We aimed to report our real-life experience with the use of remdesivir from its availability in Spain. METHODS: We performed a descriptive study of all patients admitted for >/=48 hours with confirmed COVID-19 who received remdesivir between the 1st of July and the 30th of September 2020. RESULTS: A total of 123 patients out of 242 admitted with COVID-19 at our hospital (50.8%) received remdesivir. Median age was 58 years, 61% were males and 56.9 % received at least one anti-inflammatory treatment. No adverse events requiring remdesivir discontinuation were reported. The need of intensive care unit admission, mechanical ventilation and 30-days mortality were 19.5%, 7.3% and 4.1%, respectively. CONCLUSIONS: In our real-life experience, the use of remdesivir in hospitalized patients with COVID-19 was associated with a low mortality rate and good safety profile.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Inpatients[MESH]
  • |Adenosine Monophosphate/*analogs & derivatives/therapeutic use[MESH]
  • |Aged[MESH]
  • |Alanine/*analogs & derivatives/therapeutic use[MESH]
  • |Anti-Inflammatory Agents/therapeutic use[MESH]
  • |Antibodies, Monoclonal, Humanized/therapeutic use[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |COVID-19/mortality[MESH]
  • |Cohort Studies[MESH]
  • |Dexamethasone/therapeutic use[MESH]
  • |Female[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Intensive Care Units/statistics & numerical data[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Respiration, Artificial/statistics & numerical data[MESH]
  • |Spain/epidemiology[MESH]


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