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10.3390/v13020284

http://scihub22266oqcxt.onion/10.3390/v13020284
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33673067!7918933!33673067
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suck abstract from ncbi


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pmid33673067      Viruses 2021 ; 13 (2): ä
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  • Titers of Neutralizing Antibodies against SARS-CoV-2 Are Independent of Symptoms of Non-Severe COVID-19 in Young Adults #MMPMID33673067
  • Jonsdottir HR; Bielecki M; Siegrist D; Buehrer TW; Zust R; Deuel JW
  • Viruses 2021[Feb]; 13 (2): ä PMID33673067show ga
  • Neutralizing antibodies are an important part of the humoral immune response to SARS-CoV-2. It is currently unclear to what extent such antibodies are produced after non-severe disease or asymptomatic infection. We studied a cluster of SARS-CoV-2 infections among a homogeneous population of 332 predominantly male Swiss soldiers and determined the neutralizing antibody response with a serum neutralization assay using a recombinant SARS-CoV-2-GFP. All patients with non-severe COVID-19 showed a swift humoral response within two weeks after the onset of symptoms, which remained stable for the duration of the study. One month after the outbreak, titers in COVID-19 convalescents did not differ from the titers of asymptomatically infected individuals. Furthermore, symptoms of COVID-19 did not correlate with neutralizing antibody titers. Therefore, we conclude that asymptomatic infection can induce the same humoral immunity as non-severe COVID-19 in young adults.
  • |*Asymptomatic Infections[MESH]
  • |*Immunity, Humoral[MESH]
  • |Adult[MESH]
  • |Antibodies, Neutralizing/*blood[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |COVID-19/epidemiology/*immunology[MESH]
  • |Cohort Studies[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Military Personnel[MESH]
  • |Neutralization Tests[MESH]
  • |Switzerland/epidemiology[MESH]


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