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10.3390/cells10020460 http://scihub22266oqcxt.onion/10.3390/cells10020460 33669990!7927137!33669990     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cells 2021 ; 10 (2): ä Nephropedia Template TP {{tp|p=33669990|t=2021. The Pleiotropic Function of Human Sirtuins as Modulators of Metabolic Pathways and Viral Infections |pdf=|usr=}}{{33669990}} gab.com Text The Pleiotropic Function of Human Sirtuins as Modulators of Metabolic Pathways and Viral Infections JO: Cells http://www.kidney.de/pget.php?&tw=1&pmid=33669990 #FOAvip Sirtuins (SIRTs) are nicotinamide adenine dinucleotide-dependent histone deacetylases that incorporate complex functions in the mechanisms of cell physiology. Mammals have seven distinct members of the SIRT family (SIRT1-7), which play an important role in a well-maintained network of metabolic pathways that control and adapt the cell to the environment, energy availability and cellular stress. Until recently, very few studies investigated the role of SIRTs in modulating viral infection and progeny. Recent studies have demonstrated that SIRT1 and SIRT2 are promising antiviral targets because of their specific connection to numerous metabolic and regulatory processes affected during infection. In the present review, we summarize some of the recent progress in SIRTs biochemistry and their emerging function as antiviral targets. We also discuss the potential of natural polyphenol-based SIRT modulators to control their functional roles in several diseases including viral infections. Twit Text FOAVip The Pleiotropic Function of Human Sirtuins as Modulators of Metabolic Pathways and Viral Infections ????Cells http://www.kidney.de/pget.php?&tw=1&pmid=33669990 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33669990 #FOAvip English Wikipedia <ref>{{Cite pmid|33669990}}</ref> The Pleiotropic Function of Human Sirtuins as Modulators of Metabolic Pathways and Viral Infections #MMPMID33669990 Alqarni MH; Foudah AI; Muharram MM; Labrou NE Cells 2021[Feb]; 10 (2): ä PMID33669990show ga Sirtuins (SIRTs) are nicotinamide adenine dinucleotide-dependent histone deacetylases that incorporate complex functions in the mechanisms of cell physiology. Mammals have seven distinct members of the SIRT family (SIRT1-7), which play an important role in a well-maintained network of metabolic pathways that control and adapt the cell to the environment, energy availability and cellular stress. Until recently, very few studies investigated the role of SIRTs in modulating viral infection and progeny. Recent studies have demonstrated that SIRT1 and SIRT2 are promising antiviral targets because of their specific connection to numerous metabolic and regulatory processes affected during infection. In the present review, we summarize some of the recent progress in SIRTs biochemistry and their emerging function as antiviral targets. We also discuss the potential of natural polyphenol-based SIRT modulators to control their functional roles in several diseases including viral infections. |*Metabolic Networks and Pathways/drug effects[MESH] |Animals[MESH] |Antiviral Agents/chemistry/pharmacology[MESH] |Drug Discovery[MESH] |Humans[MESH] |Models, Molecular[MESH] |Molecular Targeted Therapy[MESH] |NAD/metabolism[MESH] |Sirtuins/analysis/*metabolism[MESH] |Virus Diseases/drug therapy/*metabolism[MESH]The Pleiotropic Function of Human Sirtuins as Modulators of Metabolic (epmc).pdf DeepDyve Pubget Overpricing