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10.3390/life11030182

http://scihub22266oqcxt.onion/10.3390/life11030182
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33669011!7996623!33669011
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suck abstract from ncbi


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pmid33669011      Life+(Basel) 2021 ; 11 (3): ä
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  • How Do Inflammatory Mediators, Immune Response and Air Pollution Contribute to COVID-19 Disease Severity? A Lesson to Learn #MMPMID33669011
  • Signorini C; Pignatti P; Coccini T
  • Life (Basel) 2021[Feb]; 11 (3): ä PMID33669011show ga
  • Inflammatory and immune processes are defensive mechanisms that aim to remove harmful agents. As a response to infections, inflammation and immune response contribute to the pathophysiological mechanisms of diseases. Coronavirus disease 2019 (COVID-19), whose underlying mechanisms remain not fully elucidated, has posed new challenges for the knowledge of pathophysiology. Chiefly, the inflammatory process and immune response appear to be unique features of COVID-19 that result in developing a hyper-inflammatory syndrome, and air pollution, the world's largest health risk factor, may partly explain the behaviour and fate of COVID-19. Understanding the mechanisms involved in the progression of COVID-19 is of fundamental importance in order to avoid the late stage of the disease, associated with a poor prognosis. Here, the role of the inflammatory and immune mediators in COVID-19 pathophysiology is discussed.
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