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10.1016/j.mehy.2021.110544 http://scihub22266oqcxt.onion/10.1016/j.mehy.2021.110544 33657458!7890352!33657458     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Hypotheses 2021 ; 149 (ä): 110544 Nephropedia Template TP {{tp|p=33657458|t=2021. Autism Spectrum Disorder patients may be susceptible to COVID-19 disease due to deficiency in melatonin |pdf=|usr=}}{{33657458}} gab.com Text Autism Spectrum Disorder patients may be susceptible to COVID-19 disease due to deficiency in melatonin JO: Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=33657458 #FOAvip Patients with Autism Spectrum Disorder (ASD) may be particularly prone to develop COVID-19. An unusual extended course of COVID-19 disease illness has been reported in one ASD patient and a group of patients have COVID-19 disease in a neurodevelopmental facility. It has been widely reported that many of those with ASD have substantial sleep disorders with low levels of melatonin and various genetic alterations related to melatonin production have been found. Several lines of evidence point to a substantial role of melatonin in the body's innate defense system including acting as a scavenger, an antioxidant and modulating the immune system. We therefore hypothesize that melatonin deficiency may predispose those ASD patients who have low melatonin output to COVID-19 disease. Potential implications for treatment are discussed. Twit Text FOAVip Autism Spectrum Disorder patients may be susceptible to COVID-19 disease due to deficiency in melatonin ????Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=33657458 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33657458 #FOAvip English Wikipedia <ref>{{Cite pmid|33657458}}</ref> Autism Spectrum Disorder patients may be susceptible to COVID-19 disease due to deficiency in melatonin #MMPMID33657458 Brown GM; Karthikeyan R; Pandi-Perumal SR; Cardinali DP Med Hypotheses 2021[Apr]; 149 (ä): 110544 PMID33657458show ga Patients with Autism Spectrum Disorder (ASD) may be particularly prone to develop COVID-19. An unusual extended course of COVID-19 disease illness has been reported in one ASD patient and a group of patients have COVID-19 disease in a neurodevelopmental facility. It has been widely reported that many of those with ASD have substantial sleep disorders with low levels of melatonin and various genetic alterations related to melatonin production have been found. Several lines of evidence point to a substantial role of melatonin in the body's innate defense system including acting as a scavenger, an antioxidant and modulating the immune system. We therefore hypothesize that melatonin deficiency may predispose those ASD patients who have low melatonin output to COVID-19 disease. Potential implications for treatment are discussed. |*Disease Susceptibility[MESH] |Autism Spectrum Disorder/*complications[MESH] |COVID-19/complications/*diagnosis[MESH] |Circadian Rhythm[MESH] |Genetic Variation[MESH] |Humans[MESH] |Melatonin/*deficiency[MESH] |Models, Theoretical[MESH] |Pineal Gland/physiology[MESH] |Sleep[MESH] |Sleep Wake Disorders/complications/*diagnosis[MESH]Autism Spectrum Disorder patients may be susceptible to COVID-19 disea(epmc).pdf DeepDyve Pubget Overpricing