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10.1016/j.orcp.2021.02.006

http://scihub22266oqcxt.onion/10.1016/j.orcp.2021.02.006
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33653666!7904471!33653666
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suck abstract from ncbi


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pmid33653666      Obes+Res+Clin+Pract 2021 ; 15 (2): 172-176
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  • Association of obesity with illness severity in hospitalized patients with COVID-19: A retrospective cohort study #MMPMID33653666
  • Suresh S; Siddiqui M; Abu Ghanimeh M; Jou J; Simmer S; Mendiratta V; Russell S; Al-Shammari M; Chatfield A; Alsheik E; Dang D; Genaw J; Zuchelli T
  • Obes Res Clin Pract 2021[Mar]; 15 (2): 172-176 PMID33653666show ga
  • BACKGROUND: Although recent studies have shown an association between obesity and adverse coronavirus disease 2019 (COVID-19) patient outcomes, there is a paucity in large studies focusing on hospitalized patients. We aimed to analyze outcomes associated with obesity in a large cohort of hospitalized COVID-19 patients. METHODS: We performed a retrospective study at a tertiary care health system of adult patients with COVID-19 who were admitted between March 1 and April 30, 2020. Patients were stratified by body mass index (BMI) into obese (BMI >/= 30 kg/m 2) and non-obese (BMI < 30 kg/m 2) cohorts. Primary outcomes were mortality, intensive care unit (ICU) admission, intubation, and 30-day readmission. RESULTS: A total of 1983 patients were included of whom 1031 (51.9%) had obesity and 952 (48.9%) did not have obesity. Patients with obesity were younger (P < 0.001), more likely to be female (P < 0.001) and African American (P < 0.001) compared to patients without obesity. Multivariable logistic models adjusting for differences in age, sex, race, medical comorbidities, and treatment modalities revealed no difference in 60-day mortality and 30-day readmission between obese and non-obese groups. In these models, patients with obesity had increased odds of ICU admission (adjusted OR, 1.37; 95% CI, 1.07-1.76; P = 0.012) and intubation (adjusted OR, 1.37; 95% CI, 1.04-1.80; P = 0.026). CONCLUSIONS: Obesity in patients with COVID-19 is independently associated with increased risk for ICU admission and intubation. Recognizing that obesity impacts morbidity in this manner is crucial for appropriate management of COVID-19 patients.
  • |*Body Mass Index[MESH]
  • |*Hospitalization[MESH]
  • |*Intensive Care Units[MESH]
  • |*Severity of Illness Index[MESH]
  • |Adult[MESH]
  • |Age Factors[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*epidemiology/therapy[MESH]
  • |Comorbidity[MESH]
  • |Female[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Intubation[MESH]
  • |Logistic Models[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Obesity/*epidemiology/ethnology[MESH]
  • |Odds Ratio[MESH]
  • |Patient Readmission[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


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