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10.1080/21645515.2021.1880210 http://scihub22266oqcxt.onion/10.1080/21645515.2021.1880210 33651967!7938654!33651967     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Hum+Vaccin+Immunother 2021 ; 17 (8): 2808-2813 Nephropedia Template TP {{tp|p=33651967|t=2021. beta-glucans: wide-spectrum immune-balancing food-supplement-based enteric (beta-WIFE) vaccine adjuvant approach to COVID-19 |pdf=|usr=}}{{33651967}} gab.com Text beta-glucans: wide-spectrum immune-balancing food-supplement-based enteric (beta-WIFE) vaccine adjuvant approach to COVID-19 JO: Hum Vaccin Immunother http://www.kidney.de/pget.php?&tw=1&pmid=33651967 #FOAvip Conventional vaccines to combat COVID-19 through different approaches are at various stages of development. The complexity of COVID-19 such as the potential mutations of the virus leading to antigenic drift and the uncertainty on the duration of the immunity induced by the vaccine have hampered the efforts to control the COVID-19 pandemic. Thus, we suggest an alternative interim treatment strategy based on biological response modifier glucans such as the Aureobasidium pullulans AFO-202-derived beta-glucan, which has been reported to induce trained immunity, akin to that induced by the Bacille Calmette-Guerin vaccine, by epigenetic modifications at the central level in the bone marrow. These beta-glucans act as pathogen-associated molecular patterns, activating mucosal immunity by binding with specific pathogen recognition receptors such as dectin-1 and inducing both the adaptive and innate immunity by reaching distant lymphoid organs. beta-Glucans have also been used as immune adjuvants for vaccines such as the influenza vaccine. Therefore, until a conventional vaccine is widely available, an orally consumable vaccine adjuvant that acts like biosimilars, termed as the wide-spectrum immune-balancing food-supplement-based enteric (beta-WIFE) vaccine adjuvant approach, with well-reported safety is worth in-depth investigation and can be considered for a clinical trial. Twit Text FOAVip beta-glucans: wide-spectrum immune-balancing food-supplement-based enteric (beta-WIFE) vaccine adjuvant approach to COVID-19 ????Hum Vaccin Immunother http://www.kidney.de/pget.php?&tw=1&pmid=33651967 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33651967 #FOAvip English Wikipedia <ref>{{Cite pmid|33651967}}</ref> beta-glucans: wide-spectrum immune-balancing food-supplement-based enteric (beta-WIFE) vaccine adjuvant approach to COVID-19 #MMPMID33651967 Ikewaki N; Iwasaki M; Kurosawa G; Rao KS; Lakey-Beitia J; Preethy S; Abraham SJ Hum Vaccin Immunother 2021[Aug]; 17 (8): 2808-2813 PMID33651967show ga Conventional vaccines to combat COVID-19 through different approaches are at various stages of development. The complexity of COVID-19 such as the potential mutations of the virus leading to antigenic drift and the uncertainty on the duration of the immunity induced by the vaccine have hampered the efforts to control the COVID-19 pandemic. Thus, we suggest an alternative interim treatment strategy based on biological response modifier glucans such as the Aureobasidium pullulans AFO-202-derived beta-glucan, which has been reported to induce trained immunity, akin to that induced by the Bacille Calmette-Guerin vaccine, by epigenetic modifications at the central level in the bone marrow. These beta-glucans act as pathogen-associated molecular patterns, activating mucosal immunity by binding with specific pathogen recognition receptors such as dectin-1 and inducing both the adaptive and innate immunity by reaching distant lymphoid organs. beta-Glucans have also been used as immune adjuvants for vaccines such as the influenza vaccine. Therefore, until a conventional vaccine is widely available, an orally consumable vaccine adjuvant that acts like biosimilars, termed as the wide-spectrum immune-balancing food-supplement-based enteric (beta-WIFE) vaccine adjuvant approach, with well-reported safety is worth in-depth investigation and can be considered for a clinical trial. |*Biosimilar Pharmaceuticals[MESH] |*COVID-19[MESH] |*beta-Glucans[MESH] |Adjuvants, Immunologic[MESH] |BCG Vaccine[MESH] |Humans[MESH] |Immunity, Innate[MESH] |Pandemics[MESH] |SARS-CoV-2[MESH]beta-glucans: wide-spectrum immune-balancing food-supplement-based ent(epmc).pdf DeepDyve Pubget Overpricing