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10.1177/0963689721995455 http://scihub22266oqcxt.onion/10.1177/0963689721995455 33650894!7930651!33650894     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Transplant 2021 ; 30 (ä): 963689721995455 Nephropedia Template TP {{tp|p=33650894|t=2021. Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Severe COVID-19 |pdf=|usr=}}{{33650894}} gab.com Text Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Severe COVID-19 JO: Cell Transplant http://www.kidney.de/pget.php?&tw=1&pmid=33650894 #FOAvip During the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many critically ill patients died of severe pneumonia, acute respiratory distress syndrome (ARDS), or multiple organ dysfunction syndrome. To date, no specific treatments have been proven to be effective for coronavirus disease 2019 (COVID-19). In the animal models and clinical applications, mesenchymal stromal/stem cells (MSCs) have been shown safety and efficacy for the treatment of respiratory virus infection through their abilities of differentiation and immunomodulation. Besides, possessing several advantages of MSC-derived extracellular vesicles (EVs) over MSCs, EV-based therapy also holds potential therapeutic effects in respiratory virus infection. In this review, we summarized the basic characteristics and mechanisms of COVID-19 and MSCs, outlined some preclinical and clinical studies of MSCs or MSC-EVs for respiratory virus infection such as influenza virus and SARS-CoV-2, shed light on the common problems that we should overcome to translate MSC therapy into clinical application, and discussed some safe issues related to the use of MSCs. Twit Text FOAVip Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Severe COVID-19 ????Cell Transplant http://www.kidney.de/pget.php?&tw=1&pmid=33650894 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33650894 #FOAvip English Wikipedia <ref>{{Cite pmid|33650894}}</ref> Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Severe COVID-19 #MMPMID33650894 Xiong J; Chen L; Zhang L; Bao L; Shi Y Cell Transplant 2021[Jan]; 30 (ä): 963689721995455 PMID33650894show ga During the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many critically ill patients died of severe pneumonia, acute respiratory distress syndrome (ARDS), or multiple organ dysfunction syndrome. To date, no specific treatments have been proven to be effective for coronavirus disease 2019 (COVID-19). In the animal models and clinical applications, mesenchymal stromal/stem cells (MSCs) have been shown safety and efficacy for the treatment of respiratory virus infection through their abilities of differentiation and immunomodulation. Besides, possessing several advantages of MSC-derived extracellular vesicles (EVs) over MSCs, EV-based therapy also holds potential therapeutic effects in respiratory virus infection. In this review, we summarized the basic characteristics and mechanisms of COVID-19 and MSCs, outlined some preclinical and clinical studies of MSCs or MSC-EVs for respiratory virus infection such as influenza virus and SARS-CoV-2, shed light on the common problems that we should overcome to translate MSC therapy into clinical application, and discussed some safe issues related to the use of MSCs. |*Mesenchymal Stem Cell Transplantation[MESH] |Animals[MESH] |COVID-19/*therapy[MESH] |Clinical Trials as Topic[MESH] |Exosomes[MESH] |Extracellular Vesicles[MESH] |Humans[MESH] |Mesenchymal Stem Cells/*cytology[MESH] |Patient Safety[MESH]Mesenchymal Stromal Cell-Based Therapy: A Promising Approach for Sever(epmc).pdf DeepDyve Pubget Overpricing