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10.7554/eLife.64618 http://scihub22266oqcxt.onion/10.7554/eLife.64618 33650490!7997667!33650490     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Elife 2021 ; 10 (ä): ä Nephropedia Template TP {{tp|p=33650490|t=2021. Genomic epidemiology of COVID-19 in care homes in the east of England |pdf=|usr=}}{{33650490}} gab.com Text Genomic epidemiology of COVID-19 in care homes in the east of England JO: Elife http://www.kidney.de/pget.php?&tw=1&pmid=33650490 #FOAvip COVID-19 poses a major challenge to care homes, as SARS-CoV-2 is readily transmitted and causes disproportionately severe disease in older people. Here, 1167 residents from 337 care homes were identified from a dataset of 6600 COVID-19 cases from the East of England. Older age and being a care home resident were associated with increased mortality. SARS-CoV-2 genomes were available for 700 residents from 292 care homes. By integrating genomic and temporal data, 409 viral clusters within the 292 homes were identified, indicating two different patterns - outbreaks among care home residents and independent introductions with limited onward transmission. Approximately 70% of residents in the genomic analysis were admitted to hospital during the study, providing extensive opportunities for transmission between care homes and hospitals. Limiting viral transmission within care homes should be a key target for infection control to reduce COVID-19 mortality in this population. Twit Text FOAVip Genomic epidemiology of COVID-19 in care homes in the east of England ????Elife http://www.kidney.de/pget.php?&tw=1&pmid=33650490 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33650490 #FOAvip English Wikipedia <ref>{{Cite pmid|33650490}}</ref> Genomic epidemiology of COVID-19 in care homes in the east of England #MMPMID33650490 Hamilton WL; Tonkin-Hill G; Smith ER; Aggarwal D; Houldcroft CJ; Warne B; Meredith LW; Hosmillo M; Jahun AS; Curran MD; Parmar S; Caller LG; Caddy SL; Khokhar FA; Yakovleva A; Hall G; Feltwell T; Pinckert ML; Georgana I; Chaudhry Y; Brown CS; Goncalves S; Amato R; Harrison EM; Brown NM; Beale MA; Spencer Chapman M; Jackson DK; Johnston I; Alderton A; Sillitoe J; Langford C; Dougan G; Peacock SJ; Kwiatowski DP; Goodfellow IG; Torok ME Elife 2021[Mar]; 10 (ä): ä PMID33650490show ga COVID-19 poses a major challenge to care homes, as SARS-CoV-2 is readily transmitted and causes disproportionately severe disease in older people. Here, 1167 residents from 337 care homes were identified from a dataset of 6600 COVID-19 cases from the East of England. Older age and being a care home resident were associated with increased mortality. SARS-CoV-2 genomes were available for 700 residents from 292 care homes. By integrating genomic and temporal data, 409 viral clusters within the 292 homes were identified, indicating two different patterns - outbreaks among care home residents and independent introductions with limited onward transmission. Approximately 70% of residents in the genomic analysis were admitted to hospital during the study, providing extensive opportunities for transmission between care homes and hospitals. Limiting viral transmission within care homes should be a key target for infection control to reduce COVID-19 mortality in this population. |*Nursing Homes[MESH] |Aged, 80 and over[MESH] |COVID-19/*epidemiology/*transmission/virology[MESH] |Disease Outbreaks[MESH] |England/epidemiology[MESH] |Female[MESH] |Humans[MESH] |Infectious Disease Transmission, Patient-to-Professional[MESH] |Infectious Disease Transmission, Professional-to-Patient[MESH] |Male[MESH] |Polymorphism, Single Nucleotide[MESH] |SARS-CoV-2/*genetics[MESH] |Sequence Analysis[MESH]Genomic epidemiology of COVID-19 in care homes in the east of England (epmc).pdf DeepDyve Pubget Overpricing