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10.1016/j.intimp.2021.107485 http://scihub22266oqcxt.onion/10.1016/j.intimp.2021.107485 33647824!7909906!33647824     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+Immunopharmacol 2021 ; 94 (ä): 107485 Nephropedia Template TP {{tp|p=33647824|t=2021. Title of article: Mucosal-associated invariant T cells in lung diseases |pdf=|usr=}}{{33647824}} gab.com Text Title of article: Mucosal-associated invariant T cells in lung diseases JO: Int Immunopharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33647824 #FOAvip The lungs are directly connected to the external environment, which makes them more vulnerable to infection and injury. They are protected by the respiratory epithelium and immune cells to maintain a dynamic balance. Both innate and adaptive immune cells are involved in the pathogenesis of lung diseases. Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells, which have attracted increasing attention in recent years. Although MAIT cells account for a small part of the total immune cells in the lungs, evidence suggests that these cells are activated by T cell receptors and/or cytokine receptors and mediate immune response. They play an important role in immunosurveillance and immunity against microbial infection, and recent studies have shown that subsets of MAIT cells play a role in promoting pulmonary inflammation. Emerging data indicate that MAIT cells are involved in the immune response against SARS-CoV-2 and possible immunopathogenesis in COVID-19. Here, we introduce MAIT cell biology to clarify their role in the immune response. Then we review MAIT cells in human and murine lung diseases, including asthma, chronic obstructive pulmonary disease, pneumonia, pulmonary tuberculosis and lung cancer, and discuss their possible protective and pathological effects. MAIT cells represent an attractive marker and potential therapeutic target for disease progression, thus providing new strategies for the treatment of lung diseases. Twit Text FOAVip Title of article: Mucosal-associated invariant T cells in lung diseases ????Int Immunopharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33647824 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33647824 #FOAvip English Wikipedia <ref>{{Cite pmid|33647824}}</ref> Title of article: Mucosal-associated invariant T cells in lung diseases #MMPMID33647824 Wen X; Zhang X; Nian S; Wei G; Guo X; Yu H; Xie X; Ye Y; Yuan Q Int Immunopharmacol 2021[May]; 94 (ä): 107485 PMID33647824show ga The lungs are directly connected to the external environment, which makes them more vulnerable to infection and injury. They are protected by the respiratory epithelium and immune cells to maintain a dynamic balance. Both innate and adaptive immune cells are involved in the pathogenesis of lung diseases. Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells, which have attracted increasing attention in recent years. Although MAIT cells account for a small part of the total immune cells in the lungs, evidence suggests that these cells are activated by T cell receptors and/or cytokine receptors and mediate immune response. They play an important role in immunosurveillance and immunity against microbial infection, and recent studies have shown that subsets of MAIT cells play a role in promoting pulmonary inflammation. Emerging data indicate that MAIT cells are involved in the immune response against SARS-CoV-2 and possible immunopathogenesis in COVID-19. Here, we introduce MAIT cell biology to clarify their role in the immune response. Then we review MAIT cells in human and murine lung diseases, including asthma, chronic obstructive pulmonary disease, pneumonia, pulmonary tuberculosis and lung cancer, and discuss their possible protective and pathological effects. MAIT cells represent an attractive marker and potential therapeutic target for disease progression, thus providing new strategies for the treatment of lung diseases. |*SARS-CoV-2[MESH] |Animals[MESH] |Humans[MESH] |Lung Diseases/*immunology[MESH]Title of article: Mucosal-associated invariant T cells in lung disease(epmc).pdf DeepDyve Pubget Overpricing