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10.1016/j.jhin.2021.02.022 http://scihub22266oqcxt.onion/10.1016/j.jhin.2021.02.022 33647375!7908852!33647375     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Hosp+Infect 2021 ; 111 (ä): 107-116 Nephropedia Template TP {{tp|p=33647375|t=2021. Investigation of intra-hospital SARS-CoV-2 transmission using nanopore whole-genome sequencing |pdf=|usr=}}{{33647375}} gab.com Text Investigation of intra-hospital SARS-CoV-2 transmission using nanopore whole-genome sequencing JO: J Hosp Infect http://www.kidney.de/pget.php?&tw=1&pmid=33647375 #FOAvip BACKGROUND: During the SARS-CoV-2 pandemic, healthcare workers (HCWs) are being exposed to infection both at work and in their communities. Determining where HCWs might have been infected is challenging based on epidemiological data alone. At Akershus University Hospital, Norway, several clusters of possible intra-hospital SARS-CoV-2 transmission were identified based on routine contact tracing. AIM: To determine whether clusters of suspected intra-hospital SARS-CoV-2 transmission could be resolved by combining whole genome sequencing (WGS) of SARS-CoV-2 with contact tracing data. METHODS: Epidemiological data were collected during routine contact tracing of polymerase chain reaction-confirmed SARS-CoV-2-positive HCWs. Possible outbreaks were identified as wards with two or more infected HCWs defined as close contacts who tested positive for SARS-CoV-2 less than three weeks apart. Viral RNA from naso-/oropharyngeal samples underwent nanopore sequencing in direct compliance to the ARTIC Network protocol. FINDINGS: Five outbreaks were suspected from contact tracing. Viral consensus sequences from 24 HCWs, two patients, and seven anonymous samples were analysed. Two outbreaks were confirmed, one refuted, and two remained undetermined. One new potential outbreak was discovered. CONCLUSION: Combined with epidemiological data, nanopore WGS was a useful tool for investigating intra-hospital SARS-CoV-2 transmission. WGS helped to resolve questions about possible outbreaks and to guide local infection prevention and control measures. Twit Text FOAVip Investigation of intra-hospital SARS-CoV-2 transmission using nanopore whole-genome sequencing ????J Hosp Infect http://www.kidney.de/pget.php?&tw=1&pmid=33647375 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33647375 #FOAvip English Wikipedia <ref>{{Cite pmid|33647375}}</ref> Investigation of intra-hospital SARS-CoV-2 transmission using nanopore whole-genome sequencing #MMPMID33647375 Lovestad AH; Jorgensen SB; Handal N; Ambur OH; Aamot HV J Hosp Infect 2021[May]; 111 (ä): 107-116 PMID33647375show ga BACKGROUND: During the SARS-CoV-2 pandemic, healthcare workers (HCWs) are being exposed to infection both at work and in their communities. Determining where HCWs might have been infected is challenging based on epidemiological data alone. At Akershus University Hospital, Norway, several clusters of possible intra-hospital SARS-CoV-2 transmission were identified based on routine contact tracing. AIM: To determine whether clusters of suspected intra-hospital SARS-CoV-2 transmission could be resolved by combining whole genome sequencing (WGS) of SARS-CoV-2 with contact tracing data. METHODS: Epidemiological data were collected during routine contact tracing of polymerase chain reaction-confirmed SARS-CoV-2-positive HCWs. Possible outbreaks were identified as wards with two or more infected HCWs defined as close contacts who tested positive for SARS-CoV-2 less than three weeks apart. Viral RNA from naso-/oropharyngeal samples underwent nanopore sequencing in direct compliance to the ARTIC Network protocol. FINDINGS: Five outbreaks were suspected from contact tracing. Viral consensus sequences from 24 HCWs, two patients, and seven anonymous samples were analysed. Two outbreaks were confirmed, one refuted, and two remained undetermined. One new potential outbreak was discovered. CONCLUSION: Combined with epidemiological data, nanopore WGS was a useful tool for investigating intra-hospital SARS-CoV-2 transmission. WGS helped to resolve questions about possible outbreaks and to guide local infection prevention and control measures. |*Whole Genome Sequencing[MESH] |Adult[MESH] |COVID-19/epidemiology/*transmission[MESH] |Female[MESH] |Genome, Viral[MESH] |Health Personnel/*statistics & numerical data[MESH] |Humans[MESH] |Infectious Disease Transmission, Patient-to-Professional/*statistics & numerical data[MESH] |Male[MESH] |Middle Aged[MESH] |Nanopores[MESH] |Norway/epidemiology[MESH] |Occupational Diseases/*genetics[MESH]Investigation of intra-hospital SARS-CoV-2 transmission using nanopore(epmc).pdf DeepDyve Pubget Overpricing