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Sex-based differences in severity and mortality in COVID-19 #MMPMID33646622
Alwani M; Yassin A; Al-Zoubi RM; Aboumarzouk OM; Nettleship J; Kelly D; Al-Qudimat AR; Shabsigh R
Rev Med Virol 2021[Nov]; 31 (6): e2223 PMID33646622show ga
The current coronavirus disease (COVID-19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS-CoV and MERS-CoV, and viral infections in general. Here, we discuss the sex-disaggregated epidemiological data for COVID-19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.