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10.1007/s00234-021-02663-5

http://scihub22266oqcxt.onion/10.1007/s00234-021-02663-5
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33646336!7917373!33646336
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suck abstract from ncbi


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pmid33646336      Neuroradiology 2021 ; 63 (10): 1651-1658
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  • Distinct pattern of microsusceptibility changes on brain magnetic resonance imaging (MRI) in critically ill patients on mechanical ventilation/oxygenation #MMPMID33646336
  • Thurnher MM; Boban J; Roggla M; Staudinger T
  • Neuroradiology 2021[Oct]; 63 (10): 1651-1658 PMID33646336show ga
  • PURPOSE: Over the years, interesting SWI abnormalities in patients from intensive care units (ICU) were observed, not attributable to a specific cause and with uncertain clinical significance. Recently, multiple SWI-hypointense foci were mentioned related to neurological complications of SARS-COV-2 infection. The purpose of the study was to describe the patterns of susceptibility brain changes in critically-ill patients who underwent mechanical ventilation and/or extracorporeal membrane oxygenation (ECMO). METHODS: An institutional board-approved, retrospective study was conducted on 250 ICU patients in whom brain MRI was performed between January 2011 and May 2020. Out of 48 patients who underwent mechanical ventilation/ECMO, in fifteen patients (median age 47.7 years), the presence of SWI abnormalities was observed and described. RESULTS: Microsusceptibilities were located in white-gray matter interface, in subcortical white matter (U-fibers), and surrounding subcortical nuclei in 13/14 (92,8%) patients. In 8/14 (57,1%) patients, SWI foci were seen infratentorially. The corpus callosum was affected in ten (71,4%), internal capsule in five (35,7%), and midbrain/pons in six (42,8%) patients. CONCLUSION: We showed distinct patterns of diffuse brain SWI susceptibilities in critically-ill patients who underwent mechanical ventilation/ECMO. The etiology of these foci remains uncertain, but the association with mechanical ventilation, prolonged respiratory failure, and hypoxemia seems probable explanations.
  • |*COVID-19[MESH]
  • |*Critical Illness[MESH]
  • |Brain/diagnostic imaging[MESH]
  • |Humans[MESH]
  • |Magnetic Resonance Imaging[MESH]
  • |Middle Aged[MESH]
  • |Respiration, Artificial[MESH]
  • |Retrospective Studies[MESH]


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