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10.1186/s12882-021-02270-9 http://scihub22266oqcxt.onion/10.1186/s12882-021-02270-9 33639881!7912967!33639881     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33639881&cmd=llinks): Failed to open stream: HTTP request failed! 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Age and multimorbidities as poor prognostic factors for COVID-19 in hemodialysis: a Lebanese national study |pdf=|usr=}}{{33639881}} gab.com Text Age and multimorbidities as poor prognostic factors for COVID-19 in hemodialysis: a Lebanese national study JO: BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=33639881 #FOAvip BACKGROUND: Hemodialysis patients with COVID-19 have been reported to be at higher risk for death than the general population. Several prognostic factors have been identified in the studies from Asian, European or American countries. This is the first national Lebanese study assessing the factors associated with SARS-CoV-2 mortality in hemodialysis patients. METHODS: This is an observational study that included all chronic hemodialysis patients in Lebanon who were tested positive for SARS-CoV-2 from 31st March to 1st November 2020. Data on demographics, comorbidities, admission to hospital and outcome were collected retrospectively from the patients' medical records. A binary logistic regression analysis was performed to assess risk factors for mortality. RESULTS: A total of 231 patients were included. Mean age was 61.46 +/- 13.99 years with a sex ratio of 128 males to 103 females. Around half of the patients were diabetics, 79.2% presented with fever. A total of 115 patients were admitted to the hospital, 59% of them within the first day of diagnosis. Hypoxia was the major reason for hospitalization. Death rate was 23.8% after a median duration of 6 (IQR, 2 to 10) days. Adjusted regression analysis showed a higher risk for death among older patients (odds ratio = 1.038; 95% confidence interval: 1.013, 1.065), patients with heart failure (odds ratio = 4.42; 95% confidence interval: 2.06, 9.49), coronary artery disease (odds ratio = 3.27; 95% confidence interval: 1.69, 6.30), multimorbidities (odds ratio = 1.593; 95% confidence interval: 1.247, 2.036), fever (odds ratio = 6.66; 95% confidence interval: 1.94, 27.81), CRP above 100 mg/L (odds ratio = 4.76; 95% confidence interval: 1.48, 15.30), and pneumonia (odds ratio = 19.18; 95% confidence interval: 6.47, 56.83). CONCLUSIONS: This national study identified older age, coronary artery disease, heart failure, multimorbidities, fever and pneumonia as risk factors for death in patients with COVID-19 on chronic hemodialysis. The death rate was comparable to other countries and estimated at 23.8%. Twit Text FOAVip Age and multimorbidities as poor prognostic factors for COVID-19 in hemodialysis: a Lebanese national study ????BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=33639881 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33639881 #FOAvip English Wikipedia <ref>{{Cite pmid|33639881}}</ref> Age and multimorbidities as poor prognostic factors for COVID-19 in hemodialysis: a Lebanese national study #MMPMID33639881 Aoun M; Khalil R; Mahfoud W; Fatfat H; Bou Khalil L; Alameddine R; Afiouni N; Ibrahim I; Hassan M; Zarzour H; Jebai A; Khalil NM; Tawil L; Mechref Z; El Imad Z; Chamma F; Khalil A; Zeidan S; El Ghoul B; Dahdah G; Mouawad S; Azar H; Chahine KA; Kallab S; Moawad B; Fawaz A; Homsi J; Tabaja C; Delbani M; Kallab R; Hoballah H; Haykal W; Fares N; Rahal W; Mroueh W; Youssef M; Rizkallah J; Sebaaly Z; Dfouni A; Ghosn N; Nawfal N; Jaoude WA; Bassil N; Maroun T; Bassil N; Beaini C; Haddad B; Moubarak E; Rabah H; Attieh A; Finianos S; Chelala D BMC Nephrol 2021[Feb]; 22 (1): 73 PMID33639881show ga BACKGROUND: Hemodialysis patients with COVID-19 have been reported to be at higher risk for death than the general population. Several prognostic factors have been identified in the studies from Asian, European or American countries. This is the first national Lebanese study assessing the factors associated with SARS-CoV-2 mortality in hemodialysis patients. METHODS: This is an observational study that included all chronic hemodialysis patients in Lebanon who were tested positive for SARS-CoV-2 from 31st March to 1st November 2020. Data on demographics, comorbidities, admission to hospital and outcome were collected retrospectively from the patients' medical records. A binary logistic regression analysis was performed to assess risk factors for mortality. RESULTS: A total of 231 patients were included. Mean age was 61.46 +/- 13.99 years with a sex ratio of 128 males to 103 females. Around half of the patients were diabetics, 79.2% presented with fever. A total of 115 patients were admitted to the hospital, 59% of them within the first day of diagnosis. Hypoxia was the major reason for hospitalization. Death rate was 23.8% after a median duration of 6 (IQR, 2 to 10) days. Adjusted regression analysis showed a higher risk for death among older patients (odds ratio = 1.038; 95% confidence interval: 1.013, 1.065), patients with heart failure (odds ratio = 4.42; 95% confidence interval: 2.06, 9.49), coronary artery disease (odds ratio = 3.27; 95% confidence interval: 1.69, 6.30), multimorbidities (odds ratio = 1.593; 95% confidence interval: 1.247, 2.036), fever (odds ratio = 6.66; 95% confidence interval: 1.94, 27.81), CRP above 100 mg/L (odds ratio = 4.76; 95% confidence interval: 1.48, 15.30), and pneumonia (odds ratio = 19.18; 95% confidence interval: 6.47, 56.83). CONCLUSIONS: This national study identified older age, coronary artery disease, heart failure, multimorbidities, fever and pneumonia as risk factors for death in patients with COVID-19 on chronic hemodialysis. The death rate was comparable to other countries and estimated at 23.8%. |*Multimorbidity[MESH] |*Renal Dialysis[MESH] |Age Factors[MESH] |Aged[MESH] |COVID-19/complications/*mortality[MESH] |Coronary Disease/complications[MESH] |Critical Care[MESH] |Dementia/complications[MESH] |Female[MESH] |Fever/complications[MESH] |Heart Failure/complications[MESH] |Hospitalization[MESH] |Humans[MESH] |Lebanon/epidemiology[MESH] |Male[MESH] |Middle Aged[MESH] |Prognosis[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH]Age and multimorbidities as poor prognostic factors for COVID-19 in he(epmc).pdf DeepDyve Pubget Overpricing