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10.18632/aging.202557 http://scihub22266oqcxt.onion/10.18632/aging.202557 33638944!7993712!33638944     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Aging+(Albany+NY) 2021 ; 13 (5): 7020-7034 Nephropedia Template TP {{tp|p=33638944|t=2021. The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study |pdf=|usr=}}{{33638944}} gab.com Text The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study JO: Aging (Albany NY) http://www.kidney.de/pget.php?&tw=1&pmid=33638944 #FOAvip BACKGROUND: The inflammatory reaction is the main cause of acute respiratory distress syndrome and multiple organ failure in patients with Coronavirus disease 2019, especially those with severe and critical illness. Several studies suggested that high-dose vitamin C reduced inflammatory reaction associated with sepsis and acute respiratory distress syndrome. This study aimed to determine the efficacy and safety of high-dose vitamin C in Coronavirus disease 2019. METHODS: We included 76 patients with Coronavirus disease 2019, classified into the high-dose vitamin C group (loading dose of 6g intravenous infusion per 12 hr on the first day, and 6g once for the following 4 days, n=46) and the standard therapy group (standard therapy alone, n=30). RESULTS: The risk of 28-day mortality was reduced for the high-dose vitamin C versus the standard therapy group (HR=0.14, 95% CI, 0.03-0.72). Oxygen support status was improved more with high-dose vitamin C than standard therapy (63.9% vs 36.1%). No safety events were associated with high-dose vitamin C therapy. CONCLUSION: High-dose vitamin C may reduce the mortality and improve oxygen support status in patients with Coronavirus disease 2019 without adverse events. Twit Text FOAVip The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study ????Aging (Albany NY) http://www.kidney.de/pget.php?&tw=1&pmid=33638944 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33638944 #FOAvip English Wikipedia <ref>{{Cite pmid|33638944}}</ref> The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study #MMPMID33638944 Gao D; Xu M; Wang G; Lv J; Ma X; Guo Y; Zhang D; Yang H; Jiang W; Deng F; Xia G; Lu Z; Lv L; Gong S Aging (Albany NY) 2021[Feb]; 13 (5): 7020-7034 PMID33638944show ga BACKGROUND: The inflammatory reaction is the main cause of acute respiratory distress syndrome and multiple organ failure in patients with Coronavirus disease 2019, especially those with severe and critical illness. Several studies suggested that high-dose vitamin C reduced inflammatory reaction associated with sepsis and acute respiratory distress syndrome. This study aimed to determine the efficacy and safety of high-dose vitamin C in Coronavirus disease 2019. METHODS: We included 76 patients with Coronavirus disease 2019, classified into the high-dose vitamin C group (loading dose of 6g intravenous infusion per 12 hr on the first day, and 6g once for the following 4 days, n=46) and the standard therapy group (standard therapy alone, n=30). RESULTS: The risk of 28-day mortality was reduced for the high-dose vitamin C versus the standard therapy group (HR=0.14, 95% CI, 0.03-0.72). Oxygen support status was improved more with high-dose vitamin C than standard therapy (63.9% vs 36.1%). No safety events were associated with high-dose vitamin C therapy. CONCLUSION: High-dose vitamin C may reduce the mortality and improve oxygen support status in patients with Coronavirus disease 2019 without adverse events. |*COVID-19 Drug Treatment[MESH] |Aged[MESH] |Ascorbic Acid/administration & dosage/adverse effects/*therapeutic use[MESH] |COVID-19/diagnosis[MESH] |Dose-Response Relationship, Drug[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Retrospective Studies[MESH] |SARS-CoV-2/drug effects/isolation & purification[MESH] |Treatment Outcome[MESH]The efficiency and safety of high-dose vitamin C in patients with COVI(epmc).pdf DeepDyve Pubget Overpricing