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10.1038/s41467-021-21553-1 http://scihub22266oqcxt.onion/10.1038/s41467-021-21553-1 33637713!7910606!33637713     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2021 ; 12 (1): 1325 Nephropedia Template TP {{tp|p=33637713|t=2021. Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19 |pdf=|usr=}}{{33637713}} gab.com Text Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19 JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33637713 #FOAvip The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known to have anti-inflammatory and antithrombotic properties, have been studied in the setting of other viral infections, but their benefit has not been assessed in COVID-19. This is a retrospective analysis of patients admitted with COVID-19 from February 1(st) through May 12(th), 2020 with study period ending on June 11(th), 2020. Antecedent statin use was assessed using medication information available in the electronic medical record. We constructed a multivariable logistic regression model to predict the propensity of receiving statins, adjusting for baseline sociodemographic and clinical characteristics, and outpatient medications. The primary endpoint includes in-hospital mortality within 30 days. A total of 2626 patients were admitted during the study period, of whom 951 (36.2%) were antecedent statin users. Among 1296 patients (648 statin users, 648 non-statin users) identified with 1:1 propensity-score matching, statin use is significantly associated with lower odds of the primary endpoint in the propensity-matched cohort (OR 0.47, 95% CI 0.36-0.62, p < 0.001). We conclude that antecedent statin use in patients hospitalized with COVID-19 is associated with lower inpatient mortality. Twit Text FOAVip Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19 ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=33637713 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33637713 #FOAvip English Wikipedia <ref>{{Cite pmid|33637713}}</ref> Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19 #MMPMID33637713 Gupta A; Madhavan MV; Poterucha TJ; DeFilippis EM; Hennessey JA; Redfors B; Eckhardt C; Bikdeli B; Platt J; Nalbandian A; Elias P; Cummings MJ; Nouri SN; Lawlor M; Ranard LS; Li J; Boyle C; Givens R; Brodie D; Krumholz HM; Stone GW; Sethi SS; Burkhoff D; Uriel N; Schwartz A; Leon MB; Kirtane AJ; Wan EY; Parikh SA Nat Commun 2021[Feb]; 12 (1): 1325 PMID33637713show ga The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known to have anti-inflammatory and antithrombotic properties, have been studied in the setting of other viral infections, but their benefit has not been assessed in COVID-19. This is a retrospective analysis of patients admitted with COVID-19 from February 1(st) through May 12(th), 2020 with study period ending on June 11(th), 2020. Antecedent statin use was assessed using medication information available in the electronic medical record. We constructed a multivariable logistic regression model to predict the propensity of receiving statins, adjusting for baseline sociodemographic and clinical characteristics, and outpatient medications. The primary endpoint includes in-hospital mortality within 30 days. A total of 2626 patients were admitted during the study period, of whom 951 (36.2%) were antecedent statin users. Among 1296 patients (648 statin users, 648 non-statin users) identified with 1:1 propensity-score matching, statin use is significantly associated with lower odds of the primary endpoint in the propensity-matched cohort (OR 0.47, 95% CI 0.36-0.62, p < 0.001). We conclude that antecedent statin use in patients hospitalized with COVID-19 is associated with lower inpatient mortality. |*COVID-19 Drug Treatment[MESH] |Aged[MESH] |COVID-19/*mortality[MESH] |Female[MESH] |Hospital Mortality[MESH] |Hospitalization[MESH] |Humans[MESH] |Hydroxymethylglutaryl-CoA Reductase Inhibitors/*administration & dosage[MESH] |Logistic Models[MESH] |Male[MESH] |Middle Aged[MESH] |New York City/epidemiology[MESH] |Propensity Score[MESH] |Retrospective Studies[MESH]Association between antecedent statin use and decreased mortality in h(epmc).pdf DeepDyve Pubget Overpricing