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10.1016/j.mehy.2021.110545 http://scihub22266oqcxt.onion/10.1016/j.mehy.2021.110545 33636586!7890340!33636586     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Hypotheses 2021 ; 149 (ä): 110545 Nephropedia Template TP {{tp|p=33636586|t=2021. COVID-19-related arrhythmias and the possible effects of ranolazine |pdf=|usr=}}{{33636586}} gab.com Text COVID-19-related arrhythmias and the possible effects of ranolazine JO: Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=33636586 #FOAvip The COVID-19 pandemic has become a burden to the global healthcare community. Despite the severity of the complications associated with COVID-19, no antiviral agent is yet available for the treatment of this disease. Several studies have reported arrhythmias as one of the numerous manifestations associated with COVID-19 infection. Clinicians use different therapeutic agents in the management of COVID-19 patients with arrhythmias, apart from ranolazine; however, some of these drugs are administered with caution because of their significant side effects. In this study, we reviewed the potential antiarrhythmic effects of ranolazine in the management of cardiac arrhythmias associated with COVID-19. Ranolazine is a second-line drug approved for the treatment of chronic stable angina pectoris. Previous studies have shown that ranolazine produces its beneficial cardiac effects without any significant impact on the body's hemodynamics; hence, blood pressure is not altered. Due to its reduced side effects, ranolazine may be more effective than other drugs in producing the desired relief from COVID-19 related arrhythmias, since it produces its antiarrhythmic effect by modulating sodium, potassium and calcium channels, and suppressing cytokine expression. Twit Text FOAVip COVID-19-related arrhythmias and the possible effects of ranolazine ????Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=33636586 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33636586 #FOAvip English Wikipedia <ref>{{Cite pmid|33636586}}</ref> COVID-19-related arrhythmias and the possible effects of ranolazine #MMPMID33636586 Chukwunyere U; Sehirli AO; Abacioglu N Med Hypotheses 2021[Apr]; 149 (ä): 110545 PMID33636586show ga The COVID-19 pandemic has become a burden to the global healthcare community. Despite the severity of the complications associated with COVID-19, no antiviral agent is yet available for the treatment of this disease. Several studies have reported arrhythmias as one of the numerous manifestations associated with COVID-19 infection. Clinicians use different therapeutic agents in the management of COVID-19 patients with arrhythmias, apart from ranolazine; however, some of these drugs are administered with caution because of their significant side effects. In this study, we reviewed the potential antiarrhythmic effects of ranolazine in the management of cardiac arrhythmias associated with COVID-19. Ranolazine is a second-line drug approved for the treatment of chronic stable angina pectoris. Previous studies have shown that ranolazine produces its beneficial cardiac effects without any significant impact on the body's hemodynamics; hence, blood pressure is not altered. Due to its reduced side effects, ranolazine may be more effective than other drugs in producing the desired relief from COVID-19 related arrhythmias, since it produces its antiarrhythmic effect by modulating sodium, potassium and calcium channels, and suppressing cytokine expression. |*COVID-19 Drug Treatment[MESH] |Action Potentials[MESH] |Angina, Stable/complications[MESH] |Anti-Arrhythmia Agents/therapeutic use[MESH] |Arrhythmias, Cardiac/*complications/prevention & control[MESH] |COVID-19/*complications[MESH] |Cytokines/metabolism[MESH] |Hemodynamics[MESH] |Humans[MESH] |Inflammation[MESH] |Potassium Channels/metabolism[MESH] |Ranolazine/*therapeutic use[MESH]COVID-19-related arrhythmias and the possible effects of ranolazine (epmc).pdf DeepDyve Pubget Overpricing