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10.1021/acs.nanolett.1c00118 http://scihub22266oqcxt.onion/10.1021/acs.nanolett.1c00118 33635655!10493163!33635655     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nano+Lett 2021 ; 21 (5): 2272-2280 Nephropedia Template TP {{tp|p=33635655|t=2021. Rapid SARS-CoV-2 Spike Protein Detection by Carbon Nanotube-Based Near-Infrared Nanosensors |pdf=|usr=}}{{33635655}} gab.com Text Rapid SARS-CoV-2 Spike Protein Detection by Carbon Nanotube-Based Near-Infrared Nanosensors JO: Nano Lett http://www.kidney.de/pget.php?&tw=1&pmid=33635655 #FOAvip To effectively track and eliminate COVID-19, it is critical to develop tools for rapid and accessible diagnosis of actively infected individuals. Here, we introduce a single-walled carbon nanotube (SWCNT)-based optical sensing approach toward this end. We construct a nanosensor based on SWCNTs noncovalently functionalized with ACE2, a host protein with high binding affinity for the SARS-CoV-2 spike protein. The presence of the SARS-CoV-2 spike protein elicits a robust, 2-fold nanosensor fluorescence increase within 90 min of spike protein exposure. We characterize the nanosensor stability and sensing mechanism and passivate the nanosensor to preserve sensing response in saliva and viral transport medium. We further demonstrate that these ACE2-SWCNT nanosensors retain sensing capacity in a surface-immobilized format, exhibiting a 73% fluorescence turn-on response within 5 s of exposure to 35 mg/L SARS-CoV-2 virus-like particles. Our data demonstrate that ACE2-SWCNT nanosensors can be developed into an optical tool for rapid SARS-CoV-2 detection. Twit Text FOAVip Rapid SARS-CoV-2 Spike Protein Detection by Carbon Nanotube-Based Near-Infrared Nanosensors ????Nano Lett http://www.kidney.de/pget.php?&tw=1&pmid=33635655 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33635655 #FOAvip English Wikipedia <ref>{{Cite pmid|33635655}}</ref> Rapid SARS-CoV-2 Spike Protein Detection by Carbon Nanotube-Based Near-Infrared Nanosensors #MMPMID33635655 Pinals RL; Ledesma F; Yang D; Navarro N; Jeong S; Pak JE; Kuo L; Chuang YC; Cheng YW; Sun HY; Landry MP Nano Lett 2021[Mar]; 21 (5): 2272-2280 PMID33635655show ga To effectively track and eliminate COVID-19, it is critical to develop tools for rapid and accessible diagnosis of actively infected individuals. Here, we introduce a single-walled carbon nanotube (SWCNT)-based optical sensing approach toward this end. We construct a nanosensor based on SWCNTs noncovalently functionalized with ACE2, a host protein with high binding affinity for the SARS-CoV-2 spike protein. The presence of the SARS-CoV-2 spike protein elicits a robust, 2-fold nanosensor fluorescence increase within 90 min of spike protein exposure. We characterize the nanosensor stability and sensing mechanism and passivate the nanosensor to preserve sensing response in saliva and viral transport medium. We further demonstrate that these ACE2-SWCNT nanosensors retain sensing capacity in a surface-immobilized format, exhibiting a 73% fluorescence turn-on response within 5 s of exposure to 35 mg/L SARS-CoV-2 virus-like particles. Our data demonstrate that ACE2-SWCNT nanosensors can be developed into an optical tool for rapid SARS-CoV-2 detection. |*Nanotubes, Carbon[MESH] |Angiotensin-Converting Enzyme 2/metabolism[MESH] |Antigens, Viral/analysis[MESH] |Biosensing Techniques/*methods[MESH] |COVID-19 Testing/*methods[MESH] |COVID-19/*diagnosis/*virology[MESH] |Humans[MESH] |Immobilized Proteins/metabolism[MESH] |Nanotechnology[MESH] |Pandemics[MESH] |Protein Binding[MESH] |SARS-CoV-2/*chemistry/immunology[MESH] |Spectrometry, Fluorescence[MESH]Rapid SARS-CoV-2 Spike Protein Detection by Carbon Nanotube-Based Near(epmc).pdf DeepDyve Pubget Overpricing