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10.3389/fimmu.2020.595342 http://scihub22266oqcxt.onion/10.3389/fimmu.2020.595342 33633726!7901247!33633726     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2020 ; 11 (ä): 595342 Nephropedia Template TP {{tp|p=33633726|t=2020. Activation of the Cholinergic Anti-Inflammatory Pathway as a Novel Therapeutic Strategy for COVID-19 |pdf=|usr=}}{{33633726}} gab.com Text Activation of the Cholinergic Anti-Inflammatory Pathway as a Novel Therapeutic Strategy for COVID-19 JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33633726 #FOAvip The outbreak of coronavirus disease 2019 (COVID-19) underlined the urgent need for alleviating cytokine storm. We propose here that activating the cholinergic anti-inflammatory pathway (CAP) is a potential therapeutic strategy. However, there is currently no approved drugs targeting the regulatory pathway. It is evident that nicotine, anisodamine and some herb medicine, activate the CAP and exert anti-inflammation action in vitro and in vivo. As the vagus nerve affects both inflammation and specific immune response, we propose that vagus nerve stimulation by invasive or non-invasive devices and acupuncture at ST36, PC6, or GV20, are also feasible approaches to activate the CAP and control COVID-19. It is worth to investigate the efficacy and safety of the strategy in patients with COVID-19. Twit Text FOAVip Activation of the Cholinergic Anti-Inflammatory Pathway as a Novel Therapeutic Strategy for COVID-19 ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33633726 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33633726 #FOAvip English Wikipedia <ref>{{Cite pmid|33633726}}</ref> Activation of the Cholinergic Anti-Inflammatory Pathway as a Novel Therapeutic Strategy for COVID-19 #MMPMID33633726 Qin Z; Xiang K; Su DF; Sun Y; Liu X Front Immunol 2020[]; 11 (ä): 595342 PMID33633726show ga The outbreak of coronavirus disease 2019 (COVID-19) underlined the urgent need for alleviating cytokine storm. We propose here that activating the cholinergic anti-inflammatory pathway (CAP) is a potential therapeutic strategy. However, there is currently no approved drugs targeting the regulatory pathway. It is evident that nicotine, anisodamine and some herb medicine, activate the CAP and exert anti-inflammation action in vitro and in vivo. As the vagus nerve affects both inflammation and specific immune response, we propose that vagus nerve stimulation by invasive or non-invasive devices and acupuncture at ST36, PC6, or GV20, are also feasible approaches to activate the CAP and control COVID-19. It is worth to investigate the efficacy and safety of the strategy in patients with COVID-19. |Acupuncture[MESH] |Anti-Inflammatory Agents/pharmacology[MESH] |COVID-19/*therapy[MESH] |Cytokine Release Syndrome/*therapy[MESH] |Cytokines/blood[MESH] |Drugs, Chinese Herbal/pharmacology[MESH] |Humans[MESH] |Inflammation/therapy[MESH] |Neuroimmunomodulation/*immunology[MESH] |Nicotine/pharmacology[MESH] |SARS-CoV-2[MESH] |Solanaceous Alkaloids/pharmacology[MESH] |Vagus Nerve Stimulation/*methods[MESH]Activation of the Cholinergic Anti-Inflammatory Pathway as a Novel The(epmc).pdf DeepDyve Pubget Overpricing