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10.1021/acs.jnatprod.0c01243 http://scihub22266oqcxt.onion/10.1021/acs.jnatprod.0c01243 33631936!?!33631936       J+Nat+Prod 2021 ; 84 (2): 537-543 Nephropedia Template TP {{tp|p=33631936|t=2021. Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp |pdf=|usr=}}{{33631936}} gab.com Text Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp JO: J Nat Prod http://www.kidney.de/pget.php?&tw=1&pmid=33631936 #FOAvip A new bafilomycin derivative (1) and another seven known bafilomycins (2-8) were isolated from feces-derived Streptomyces sp. HTL16. The structure of 1 was elucidated by 1D and 2D NMR spectroscopic analysis. Biological testing demonstrated that these bafilomycins exhibited potent antiviral activities against the influenza A and SARS-CoV-2 viruses, with IC(50) values in the nanomolar range, by inhibiting the activity of endosomal ATP-driven proton pumps. Twit Text FOAVip Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp ????J Nat Prod http://www.kidney.de/pget.php?&tw=1&pmid=33631936 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33631936 #FOAvip English Wikipedia <ref>{{Cite pmid|33631936}}</ref> Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp #MMPMID33631936 Xie X; Lu S; Pan X; Zou M; Li F; Lin H; Hu J; Fan S; He J J Nat Prod 2021[Feb]; 84 (2): 537-543 PMID33631936show ga A new bafilomycin derivative (1) and another seven known bafilomycins (2-8) were isolated from feces-derived Streptomyces sp. HTL16. The structure of 1 was elucidated by 1D and 2D NMR spectroscopic analysis. Biological testing demonstrated that these bafilomycins exhibited potent antiviral activities against the influenza A and SARS-CoV-2 viruses, with IC(50) values in the nanomolar range, by inhibiting the activity of endosomal ATP-driven proton pumps. |Animals[MESH] |Antiviral Agents/*pharmacology[MESH] |Dogs[MESH] |Feces/*microbiology[MESH] |Influenza A virus/drug effects[MESH] |Macrolides/*pharmacology[MESH] |Madin Darby Canine Kidney Cells[MESH] |Proton-Translocating ATPases/*antagonists & inhibitors[MESH] |SARS-CoV-2/drug effects[MESH]Antiviral Bafilomycins from a Feces-Inhabiting Streptomyces sp (epmc).pdf DeepDyve Pubget Overpricing