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10.1016/j.cell.2021.02.010 http://scihub22266oqcxt.onion/10.1016/j.cell.2021.02.010 33631096!7871851!33631096     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell 2021 ; 184 (7): 1858-1864.e10 Nephropedia Template TP {{tp|p=33631096|t=2021. Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection |pdf=|usr=}}{{33631096}} gab.com Text Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection JO: Cell http://www.kidney.de/pget.php?&tw=1&pmid=33631096 #FOAvip Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread within the human population. Although SARS-CoV-2 is a novel coronavirus, most humans had been previously exposed to other antigenically distinct common seasonal human coronaviruses (hCoVs) before the coronavirus disease 2019 (COVID-19) pandemic. Here, we quantified levels of SARS-CoV-2-reactive antibodies and hCoV-reactive antibodies in serum samples collected from 431 humans before the COVID-19 pandemic. We then quantified pre-pandemic antibody levels in serum from a separate cohort of 251 individuals who became PCR-confirmed infected with SARS-CoV-2. Finally, we longitudinally measured hCoV and SARS-CoV-2 antibodies in the serum of hospitalized COVID-19 patients. Our studies indicate that most individuals possessed hCoV-reactive antibodies before the COVID-19 pandemic. We determined that approximately 20% of these individuals possessed non-neutralizing antibodies that cross-reacted with SARS-CoV-2 spike and nucleocapsid proteins. These antibodies were not associated with protection against SARS-CoV-2 infections or hospitalizations, but they were boosted upon SARS-CoV-2 infection. Twit Text FOAVip Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection ????Cell http://www.kidney.de/pget.php?&tw=1&pmid=33631096 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33631096 #FOAvip English Wikipedia <ref>{{Cite pmid|33631096}}</ref> Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection #MMPMID33631096 Anderson EM; Goodwin EC; Verma A; Arevalo CP; Bolton MJ; Weirick ME; Gouma S; McAllister CM; Christensen SR; Weaver J; Hicks P; Manzoni TB; Oniyide O; Ramage H; Mathew D; Baxter AE; Oldridge DA; Greenplate AR; Wu JE; Alanio C; D'Andrea K; Kuthuru O; Dougherty J; Pattekar A; Kim J; Han N; Apostolidis SA; Huang AC; Vella LA; Kuri-Cervantes L; Pampena MB; Betts MR; Wherry EJ; Meyer NJ; Cherry S; Bates P; Rader DJ; Hensley SE Cell 2021[Apr]; 184 (7): 1858-1864.e10 PMID33631096show ga Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread within the human population. Although SARS-CoV-2 is a novel coronavirus, most humans had been previously exposed to other antigenically distinct common seasonal human coronaviruses (hCoVs) before the coronavirus disease 2019 (COVID-19) pandemic. Here, we quantified levels of SARS-CoV-2-reactive antibodies and hCoV-reactive antibodies in serum samples collected from 431 humans before the COVID-19 pandemic. We then quantified pre-pandemic antibody levels in serum from a separate cohort of 251 individuals who became PCR-confirmed infected with SARS-CoV-2. Finally, we longitudinally measured hCoV and SARS-CoV-2 antibodies in the serum of hospitalized COVID-19 patients. Our studies indicate that most individuals possessed hCoV-reactive antibodies before the COVID-19 pandemic. We determined that approximately 20% of these individuals possessed non-neutralizing antibodies that cross-reacted with SARS-CoV-2 spike and nucleocapsid proteins. These antibodies were not associated with protection against SARS-CoV-2 infections or hospitalizations, but they were boosted upon SARS-CoV-2 infection. |*Antibodies, Viral/blood/immunology[MESH] |Adolescent[MESH] |Adult[MESH] |Alphacoronavirus/*immunology[MESH] |Animals[MESH] |Betacoronavirus/*immunology[MESH] |COVID-19 Serological Testing[MESH] |COVID-19/*immunology[MESH] |Child[MESH] |Child, Preschool[MESH] |Chlorocebus aethiops[MESH] |Cross Protection[MESH] |Cross Reactions[MESH] |Disease Susceptibility[MESH] |HEK293 Cells[MESH] |Humans[MESH] |Infant[MESH] |Infant, Newborn[MESH]Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infe(epmc).pdf DeepDyve Pubget Overpricing