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10.1002/bit.27729

http://scihub22266oqcxt.onion/10.1002/bit.27729
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33629351!8014656!33629351
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suck abstract from ncbi


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pmid33629351      Biotechnol+Bioeng 2021 ; 118 (6): 2168-2183
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  • Efficacy of mesenchymal stromal cells and cellular products in improvement of symptoms for COVID-19 and similar lung diseases #MMPMID33629351
  • Banimohamad-Shotorbani B; Farajpour H; Sefat F; Khosroshahi SA; Shafaei H; Heidari Keshel S
  • Biotechnol Bioeng 2021[Jun]; 118 (6): 2168-2183 PMID33629351show ga
  • At the end of 2019, respiratory coronavirus diseases 2019 (COVID-19) appeared and spread rapidly in the world. Besides several mutations, the outcome of this pandemic was the death up to 15% of hospitalized patients. Mesenchymal stromal cell therapy as a therapeutic strategy seemed successful in treatment of several diseases. Not only mesenchymal stromal cells of several tissues, but also their secreted extracellular vesicles and even secretome indicated beneficial therapeutic function. All of these three options were studied for treatment of COVID-19 as well as those respiratory diseases that have similar symptom. Fortunately, most of the outcomes were promising and optimistic. In this paper, we review in-vivo and clinical studies which have been used different sources of mesenchymal stromal cell, secreted extracellular vesicles, and secretome to improve and treat symptoms of COVID-19 and similar lung diseases.
  • |*Mesenchymal Stem Cell Transplantation[MESH]
  • |Animals[MESH]
  • |COVID-19/*therapy[MESH]
  • |Extracellular Vesicles/*transplantation[MESH]
  • |Humans[MESH]
  • |Lung Diseases/therapy[MESH]


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