Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Int+J+Microbiol 2021 ; 2021 (ä): 6643333 Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Profiling Laboratory Biomarkers Associated with COVID-19 Disease Progression: A Single-Center Experience #MMPMID33628256
Khan M; Shah N; Mushtaq H; Jehanzeb V
Int J Microbiol 2021[]; 2021 (ä): 6643333 PMID33628256show ga
BACKGROUND: There is clinical importance to investigate the disease progression through potential biomarkers of SARS-CoV-2 infection. In the present study, we aim to evaluate the significance of inflammatory markers in different categories of COVID-19 in admitted patients. METHODS: In a single-center, observational study of 50 in-hospital patients who were diagnosed with COVID-19 and admitted to the intensive care unit of a tertiary care hospital in Peshawar, infection biomarkers, including hs-CRP, serum ferritin, serum creatinine, ALT, ALP, cardiac troponin-I, and IL-6 were analyzed. RESULTS: The median age was 61.3 years. 70% (35) were male while 30% (15) were female. We noted significantly increased hs-CRP (9.32 mg/dL +/- 10.03) and ferritin levels (982.3 ng/ml +/- 601.9). A noteworthy increase was observed in neutrophil count (11.05 x 10(9)/L) and a decrease was observed in lymphocyte count (0.27 x 10(9/)L) (P < 0.05), and the platelet count was borderline decreased (244.1 x 10(9)/L). IL-6 levels were markedly increased in all admitted patients (100.2 pg/ml +/- 122.2 pg/ml). CONCLUSION: The serum levels of CRP, troponin-I, ALP, ALT, serum creatinine, and ferritin are markedly increased in COVID-19 patients. Increased CRP and ferritin levels were also associated with secondary bacterial infection and poor clinical outcomes.