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10.1186/s12890-021-01413-w http://scihub22266oqcxt.onion/10.1186/s12890-021-01413-w 33627118!7903375!33627118     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33627118&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       BMC+Pulm+Med 2021 ; 21 (1): 64 Nephropedia Template TP {{tp|p=33627118|t=2021. Elevated glucose level leads to rapid COVID-19 progression and high fatality |pdf=|usr=}}{{33627118}} gab.com Text Elevated glucose level leads to rapid COVID-19 progression and high fatality JO: BMC Pulm Med http://www.kidney.de/pget.php?&tw=1&pmid=33627118 #FOAvip OBJECTIVES: We aimed to identify high-risk factors for disease progression and fatality for coronavirus disease 2019 (COVID-19) patients. METHODS: We enrolled 2433 COVID-19 patients and used LASSO regression and multivariable cause-specific Cox proportional hazard models to identify the risk factors for disease progression and fatality. RESULTS: The median time for progression from mild-to-moderate, moderate-to-severe, severe-to-critical, and critical-to-death were 3.0 (interquartile range: 1.8-5.5), 3.0 (1.0-7.0), 3.0 (1.0-8.0), and 6.5 (4.0-16.3) days, respectively. Among 1,758 mild or moderate patients at admission, 474 (27.0%) progressed to a severe or critical stage. Age above 60 years, elevated levels of blood glucose, respiratory rate, fever, chest tightness, c-reaction protein, lactate dehydrogenase, direct bilirubin, and low albumin and lymphocyte count were significant risk factors for progression. Of 675 severe or critical patients at admission, 41 (6.1%) died. Age above 74 years, elevated levels of blood glucose, fibrinogen and creatine kinase-MB, and low plateleta count were significant risk factors for fatality. Patients with elevated blood glucose level were 58% more likely to progress and 3.22 times more likely to die of COVID-19. CONCLUSIONS: Older age, elevated glucose level, and clinical indicators related to systemic inflammatory responses and multiple organ failures, predict both the disease progression and the fatality of COVID-19 patients. Twit Text FOAVip Elevated glucose level leads to rapid COVID-19 progression and high fatality ????BMC Pulm Med http://www.kidney.de/pget.php?&tw=1&pmid=33627118 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33627118 #FOAvip English Wikipedia <ref>{{Cite pmid|33627118}}</ref> Elevated glucose level leads to rapid COVID-19 progression and high fatality #MMPMID33627118 Wang W; Shen M; Tao Y; Fairley CK; Zhong Q; Li Z; Chen H; Ong JJ; Zhang D; Zhang K; Xing N; Guo H; Qin E; Guan X; Yang F; Zhang S; Zhang L; He K BMC Pulm Med 2021[Feb]; 21 (1): 64 PMID33627118show ga OBJECTIVES: We aimed to identify high-risk factors for disease progression and fatality for coronavirus disease 2019 (COVID-19) patients. METHODS: We enrolled 2433 COVID-19 patients and used LASSO regression and multivariable cause-specific Cox proportional hazard models to identify the risk factors for disease progression and fatality. RESULTS: The median time for progression from mild-to-moderate, moderate-to-severe, severe-to-critical, and critical-to-death were 3.0 (interquartile range: 1.8-5.5), 3.0 (1.0-7.0), 3.0 (1.0-8.0), and 6.5 (4.0-16.3) days, respectively. Among 1,758 mild or moderate patients at admission, 474 (27.0%) progressed to a severe or critical stage. Age above 60 years, elevated levels of blood glucose, respiratory rate, fever, chest tightness, c-reaction protein, lactate dehydrogenase, direct bilirubin, and low albumin and lymphocyte count were significant risk factors for progression. Of 675 severe or critical patients at admission, 41 (6.1%) died. Age above 74 years, elevated levels of blood glucose, fibrinogen and creatine kinase-MB, and low plateleta count were significant risk factors for fatality. Patients with elevated blood glucose level were 58% more likely to progress and 3.22 times more likely to die of COVID-19. CONCLUSIONS: Older age, elevated glucose level, and clinical indicators related to systemic inflammatory responses and multiple organ failures, predict both the disease progression and the fatality of COVID-19 patients. |*Disease Progression[MESH] |Adult[MESH] |Age Factors[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Bilirubin/blood[MESH] |Blood Glucose/*metabolism[MESH] |C-Reactive Protein/metabolism[MESH] |COVID-19/*blood/*mortality[MESH] |China/epidemiology[MESH] |Critical Illness[MESH] |Female[MESH] |Fever/virology[MESH] |Humans[MESH] |Hyperglycemia/*blood/complications[MESH] |L-Lactate Dehydrogenase/blood[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Middle Aged[MESH] |Proportional Hazards Models[MESH] |Retrospective Studies[MESH] |SARS-CoV-2[MESH] |Serum Albumin/metabolism[MESH]Elevated glucose level leads to rapid COVID-19 progression and high fa(epmc).pdf DeepDyve Pubget Overpricing