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10.1371/journal.pone.0247414

http://scihub22266oqcxt.onion/10.1371/journal.pone.0247414
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33626065!7904135!33626065
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suck abstract from ncbi


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pmid33626065      PLoS+One 2021 ; 16 (2): e0247414
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  • The effects of wearing facemasks on oxygenation and ventilation at rest and during physical activity #MMPMID33626065
  • Shein SL; Whitticar S; Mascho KK; Pace E; Speicher R; Deakins K
  • PLoS One 2021[]; 16 (2): e0247414 PMID33626065show ga
  • BACKGROUND: Facemasks are recommended to reduce the spread of SARS-CoV-2, but concern about inadequate gas exchange is an often cited reason for non-compliance. RESEARCH QUESTION: Among adult volunteers, do either cloth masks or surgical masks impair oxygenation or ventilation either at rest or during physical activity? STUDY DESIGN AND METHODS: With IRB approval and informed consent, we measured heart rate (HR), transcutaneous carbon dioxide (CO2) tension and oxygen levels (SpO2) at the conclusion of six 10-minute phases: sitting quietly and walking briskly without a mask, sitting quietly and walking briskly while wearing a cloth mask, and sitting quietly and walking briskly while wearing a surgical mask. Brisk walking required at least a 10bpm increase in heart rate. Occurrences of hypoxemia (decrease in SpO2 of >/=3% from baseline to a value of /=5 mmHg from baseline to a value of >/=46 mmHg) in individual subjects were collected. Wilcoxon signed-rank was used for pairwise comparisons among values for the whole cohort (e.g. walking without a mask versus walking with a cloth mask). RESULTS: Among 50 adult volunteers (median age 33 years; 32% with a co-morbidity), there were no episodes of hypoxemia or hypercarbia (0%; 95% confidence interval 0-1.9%). In paired comparisons, there were no statistically significant differences in either CO2 or SpO2 between baseline measurements without a mask and those while wearing either kind of mask mask, both at rest and after walking briskly for ten minutes. INTERPRETATION: The risk of pathologic gas exchange impairment with cloth masks and surgical masks is near-zero in the general adult population.
  • |*Masks/adverse effects[MESH]
  • |Adult[MESH]
  • |COVID-19/*prevention & control/psychology/transmission[MESH]
  • |Carbon Dioxide/metabolism[MESH]
  • |Exercise/physiology[MESH]
  • |Female[MESH]
  • |Heart Rate/physiology[MESH]
  • |Humans[MESH]
  • |Hypoxia/etiology/metabolism[MESH]
  • |Male[MESH]
  • |N95 Respirators/adverse effects[MESH]
  • |Oxygen/*metabolism[MESH]
  • |Pulmonary Ventilation/*physiology[MESH]
  • |Rest/physiology[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]


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