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10.1007/s43440-021-00235-1

http://scihub22266oqcxt.onion/10.1007/s43440-021-00235-1
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33625686!7903365!33625686
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suck abstract from ncbi


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pmid33625686      Pharmacol+Rep 2021 ; 73 (3): 781-785
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  • Evaluation of effects of chronic nasal steroid use on rhinological symptoms of COVID-19 with SNOT-22 questionnaire #MMPMID33625686
  • Islek A; Balci MK
  • Pharmacol Rep 2021[Jun]; 73 (3): 781-785 PMID33625686show ga
  • BACKGROUND: The benefits of corticosteroids for the treatment of COVID-19 infection are documented in the literature. The goal of the study is to compare the severity of rhinological symptoms of COVID-19 between patients with nasal steroid use (NSU) and the control group (CG) using the sino-nasal outcome test (SNOT-22) questionnaire. METHODS: A face-to-face survey was conducted at a second referral state hospital between. Patients with a complete recovery from COVID-19 were included in NSU and CG groups. Two subscales of the SNOT-22 were filled by the patients. The frequency and duration of smell and taste loss and SNOT-22 scores were compared between the two groups. RESULTS: Forty-seven patients were included in the study. Thirty-one patients were in CG and 16 patients in the NSU group. Twenty-four (51.1%) patients were females and 23 (48.9%) were males. The mean age was 41.4 +/- 8.6 years. Olfactory dysfunction was detected in 12 (75%) patients in the NSU group, and 31 (93.3%) patients in the control group (CG). Gustatory dysfunction was seen in 10 (62.5%) patients in the NSU group and 24 (77.4%) patients NSU group. (p = 0.071, 0.279, respectively). The duration of the olfactory (6.6 +/- 2.5 days) and gustatory dysfunction (6.1 +/- 2.6 days) and the mean SNOT-22 total score (11.9 +/- 1.6) was significantly lower in the NSU group (p < 0.001, CI 11.1-5.1, CI 9.9-4.6, CI 9.3-5.9, respectively). CONCLUSIONS: Although nasal steroid use does not prevent olfactory and gustatory dysfunction in COVID-19 patients, it may reduce the severity and duration of these symptoms.
  • |*COVID-19 Drug Treatment[MESH]
  • |Adult[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Olfaction Disorders/*drug therapy/virology[MESH]
  • |SARS-CoV-2[MESH]
  • |Sino-Nasal Outcome Test[MESH]
  • |Smell/drug effects[MESH]
  • |Steroids/*therapeutic use[MESH]
  • |Surveys and Questionnaires[MESH]


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