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10.1080/14760584.2021.1891888 http://scihub22266oqcxt.onion/10.1080/14760584.2021.1891888 33624568!ä!33624568 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Vaccines 2021 ; 20 (4): 465-481 Nephropedia Template TP {{tp|p=33624568|t=2021. Hypothetical emergence of poliovirus in 2020: part 1 Consequences of policy decisions to respond using nonpharmaceutical interventions |pdf=|usr=}}{{33624568}} gab.com Text Hypothetical emergence of poliovirus in 2020: part 1 Consequences of policy decisions to respond using nonpharmaceutical interventions JO: Expert Rev Vaccines http://www.kidney.de/pget.php?&tw=1&pmid=33624568 #FOAvip OBJECTIVES: As efforts to control COVID-19 continue, we simulate hypothetical emergence of wild poliovirus assuming an immunologically naive population. This differs from the current global experience with polio and serves as a model for responding to future pandemics. METHODS: Applying an established global model, we assume a fully susceptible global population to polioviruses, independently introduce a virus with properties of each of the three stable wild poliovirus serotypes, and explore the impact of strategies that range from doing nothing to seeking global containment and eradication. RESULTS: We show the dynamics of paralytic cases as the virus spreads globally. We demonstrate the difficulty of eradication unless aggressive efforts begin soon after initial disease detection. Different poliovirus serotypes lead to different trajectories and burdens of disease. In the absence of aggressive measures, the virus would become globally endemic in 2-10 years, and cumulative paralytic cases would exceed 4-40 million depending on serotype, with the burden of disease shifting to younger ages. CONCLUSIONS: The opportunity to eradicate emerging infections represents an important public policy choice. If the world first observed the emergence of wild poliovirus in 2020, adopting aggressive control strategies would have been required to prevent a devastating global pandemic. Twit Text FOAVip Hypothetical emergence of poliovirus in 2020: part 1 Consequences of policy decisions to respond using nonpharmaceutical interventions ????Expert Rev Vaccines http://www.kidney.de/pget.php?&tw=1&pmid=33624568 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33624568 #FOAvip English Wikipedia <ref>{{Cite pmid|33624568}}</ref> Hypothetical emergence of poliovirus in 2020: part 1 Consequences of policy decisions to respond using nonpharmaceutical interventions #MMPMID33624568 Thompson KM; Kalkowska DA; Badizadegan K Expert Rev Vaccines 2021[Apr]; 20 (4): 465-481 PMID33624568show ga OBJECTIVES: As efforts to control COVID-19 continue, we simulate hypothetical emergence of wild poliovirus assuming an immunologically naive population. This differs from the current global experience with polio and serves as a model for responding to future pandemics. METHODS: Applying an established global model, we assume a fully susceptible global population to polioviruses, independently introduce a virus with properties of each of the three stable wild poliovirus serotypes, and explore the impact of strategies that range from doing nothing to seeking global containment and eradication. RESULTS: We show the dynamics of paralytic cases as the virus spreads globally. We demonstrate the difficulty of eradication unless aggressive efforts begin soon after initial disease detection. Different poliovirus serotypes lead to different trajectories and burdens of disease. In the absence of aggressive measures, the virus would become globally endemic in 2-10 years, and cumulative paralytic cases would exceed 4-40 million depending on serotype, with the burden of disease shifting to younger ages. CONCLUSIONS: The opportunity to eradicate emerging infections represents an important public policy choice. If the world first observed the emergence of wild poliovirus in 2020, adopting aggressive control strategies would have been required to prevent a devastating global pandemic. |*Global Health[MESH] |COVID-19/epidemiology/immunology/prevention & control[MESH] |Disease Eradication/methods/trends[MESH] |Disease Outbreaks/prevention & control[MESH] |Health Policy/*trends[MESH] |Humans[MESH] |Poliomyelitis/*epidemiology/immunology/prevention & control[MESH] |Poliovirus/*isolation & purification[MESH]Hypothetical emergence of poliovirus in 2020: part 1 Consequences of (epmc).pdf DeepDyve Pubget Overpricing